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TranscriptomicsHepatic transcriptome in wild-type and LXR-deficient mice
LXR is a transcription factor. Two isoforms exist in mice (alpha and beta). They are both expressed in the liver. We examined the role of LXR by obtaining gene expression profiles from the livers of wild-type and LXR-/- mice from the same genetic background. Liver gene expression was measured from m...
ORGANISM(S): Mus musculus 
2012-11-07 | E-GEOD-38083 | biostudies-arrayexpress
UnknownActivation of the cGAS-STING innate immune response in cells with deficient mitochondrial topoisomerase TOP1MT.
Not available
S-EPMC10360396 | biostudies-literature
TranscriptomicsReplication initiation sites in cancer cells
Reads from massively parallel sequencing of RNA primed, short nascent strands from asynchronously growing cancer cells (K562, MCF7). Newly replicated DNA was isolated based on size (400-800 bp) and the presence of a short RNA stretch at the 5' end using lambda exonuclease. Purified nascent strands w...
ORGANISM(S): Homo sapiens 
2011-08-02 | E-GEOD-28911 | biostudies-arrayexpress
TranscriptomicsA high-resolution transcriptome map of Ectocarpus siliculosus
Brown algae (Phaeophyceae) are complex photosynthetic organisms with a very different evolutionary history to green plants, to which they are only distantly related. These seaweeds are the dominant species in rocky coastal ecosystems and they exhibit many interesting adaptations to these, often hars...
ORGANISM(S): Ectocarpus siliculosus 
2010-04-07 | E-GEOD-19912 | biostudies-arrayexpress
UnknownExploitation of the chick embryo chorioallantoic membrane (CAM) as a platform for anti-metastatic drug testing.
Not available
S-EPMC7547099 | biostudies-literature
ProteomicsImmunoprecipitated PARP1 interactome
Poly-(ADP-ribose) polymerase inhibitors (PARPi) elicit anti-tumour activity in homologous recombination defective cancers by promoting cytotoxic, chromatin-bound, “trapped” PARP1 DNA lesions. How cells process trapped PARP1 remains unclear. By exploiting wild-type or trapping-resistant PARP1 transge...
ORGANISM(S): Homo sapiens (Human) 
2021-10-05 | PXD024337 | Pride
Trapped parp1 Breast cancer Parp1 Rime Vcp Apex2 proximity labelling 
UnknownEfficiency and effectiveness of intensive multidisciplinary follow-up of patients with stroke/TIA or myocardial infarction compared to usual monitoring: protocol of a pragmatic randomised clinical trial. DiVa (Dijon vascular) study.
Not available
S-EPMC10151851 | biostudies-literature
UnknownIdentification of Schlafen-11 as a Target of CD47 Signaling That Regulates Sensitivity to Ionizing Radiation and Topoisomerase Inhibitors.
Not available
S-EPMC6781860 | biostudies-literature
UnknownTopoisomerase III-beta protects from immune dysregulation and tumorigenesis.
Not available
S-EPMC12716394 | biostudies-literature
UnknownGenomic and evolutionary classification of lung cancer in never smokers.
Not available
S-EPMC8432745 | biostudies-literature
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