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ProteomicsLoss-less nano-fractionator for high sensitivity, high coverage proteomics
Recent advances in mass spectrometry (MS)-based proteomics now allow very deep coverage of cellular proteomes. To achieve near-comprehensive identification and quantification, the combination of a first HPLC-based peptide fractionation orthogonal to the online LC-MS/MS step has proven to be particul...
ORGANISM(S): Homo sapiens (Human) 
2017-04-11 | PXD005141 | Pride
Fractionation Cell lines Nano-flow 
ProteomicsA large-scale proteomic identification of targets of cellular miR-197 downregulated by enterovirus A71
MicroRNAs are noncoding RNA species comprising 18–23 nucleotides that regulate host-virus interaction networks. Here, we showed that enterovirus A71 infection in human rhabdomyosarcoma (RD) involved miR-197 expression. miR-197 can regulate virus replication in the context of viral RNA synthesis via ...
ORGANISM(S): Homo sapiens (Human) 
2018-10-24 | PXD010585 | Pride
Viral replication Targetscan Microrna Silac Mir-197 Enterovirus a71 
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