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The expression profiles were determined using Affymetrix ATH1 arrays. Comparisons among the Col-0, ARF10 and mARF10 sample groups allow the identification of genes regulated by ARF10. Experiment Overall Design: Germinating seeds (22 hr imbibition) from three independent biological replicates of Col-...
ORGANISM(S): Arabidopsis thaliana 
GATA6 is a transcription factor involved in the differentiation of intestinal epithelial cells into differentiated absorptive epithelial cells. GATA6 is expressed in all segments of the small intestine. We examined the impact of deleting GATA6 from intestinal epithelial cells of the adult ileum 6-8...
ORGANISM(S): Mus musculus 
Elevated brain levels of the essential metals manganese (Mn), copper, or iron induce motor disease. However, mechanisms of metal-induced motor disease are unclear and treatments are lacking. Elucidating the mechanisms of Mn-induced motor disease is particularly important because occupational and env...
2025-03-31 | MTBLS975 | MetaboLights
Background & Aims Patient-derived gastrointestinal organoids are powerful tools for studying human physiology and disease. However, generating organoids requires prompt isolation and culture of fresh tissue, which is labor and time intensive, placing restraints on basic and clinical research. For ex...
ORGANISM(S): Homo sapiens 
To determine the extent to which the major small RNA pathways functions across the Arabidopsis thaliana genome, small RNA populations from several tissues of wild-type (wt) and mutant plants were amplified by RT-PCR and sequenced using high-throughput 454 sequencing technology. Keywords: small RNAs,...
ORGANISM(S): Arabidopsis thaliana 
A single gene can give rise to multiple functionally distinct forms of protein molecules, called proteoforms, originating from gene mutations, RNA alternative splicing, polymorphisms, and post-translational modifications (PTMs). It is essential to characterize proteins in a proteoform-specific manne...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2025-12-18 | PXD059108 | Pride
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