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Introduction: The analysis of post-mortem metabolomic changes in biological fluids opens the way to develop new methods for the estimation of post-mortem interval (PMI). It may also help in the analysis of disease-induced metabolomic changes in human tissues when the postoperational samples are comp...
2017-08-23 | MTBLS349 | MetaboLights

INTRODUCTION: Application of metabolomic methods to forensic studies may expand the limits of the post-mortem interval (PMI) estimation, and improve the accuracy of the estimation. To this end, it is important to determine which tissue is the most suitable for analysis, and which...

2021-02-02 | MTBLS1518 | MetaboLights
MicroRNAs transcriptome analysis at the post-mortem interval estimation
Schizophrenia (SCZ) is a common, disabling mental illness with high heritability but complex, poorly understood genetic etiology. As the first phase of a genomic convergence analysis of SCZ, we generated 16.7 billion nucleotides of short read, shotgun sequences of cDNA from post-mortem cerebellar c...
ORGANISM(S): Homo sapiens 
To identify potential microRNA candidates for the post mortem interval estimation using a transcriptome-based approach, we extracted total RNAs from myocardial tissue samples of BALB/c mice
ORGANISM(S): Mus musculus 
2025-11-27 | GSE282991 | GEO
Genomics
Post-Mortem Interval Estimation via Microbiome
Recent developments in liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS)-based proteomics have drastically increased analytical depth and sample throughput, establishing a robust tool for comprehensive system-wide analyses. Such analyses are instrumental in studying the pathophysi...
ORGANISM(S): Mus musculus (Mouse) 
2024-12-17 | PXD053048 | Pride
Proteomic characterization of human brain tissue is increasingly utilized to identify potential novel biomarker and drug targets for a variety of neurological diseases. In whole tissue studies, results may be driven by changes in the proportion of the largest and most abundant organelles or tissue c...
ORGANISM(S): Homo sapiens (Human) 
2022-05-06 | PXD027456 | Pride
Extending the post-mortem interval (PMI) from 12- to 18-hours was done to see if transcript and protein abundance in the human retina changed. Donor eyes were recovered from post-mortem donors (n=7 pairs) and stored at 2–8°C. Only donor eyes with ocular cooling within 8 hours of death were examined....
ORGANISM(S): Homo sapiens (Human) 
2026-04-07 | PXD068030 | Pride
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