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The circadian clock is intricately connected with metabolism, however the precise details of these connections are incomplete. Here we used high temporal resolution metabolite profiling to determine circadian regulation of mouse liver and cell autonomous metabolism. In mouse liver, we found ~50% of ...
2017-04-05 | MTBLS292 | MetaboLights
Bacterial physiology in general and the bacterial response to the presence of nutrients and to external signals in particular is regulated at different levels, from mRNA synthesis to translational regulation and protein modification. However, there are not standardized parameters for defining post-t...
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2018-11-13 | PXD009809 | Pride
The mammalian TET dioxygenases contribute to global waves of DNA demethylation in the zygote and in primordial germ cells, but their involvement during de novo DNA methylation at peri/post-implantation development is unknown. Here, we show novel physiological functions of Tet1 in the pre-primitive s...
ORGANISM(S): Mus musculus 
Even though proteins are produced from mRNA, the correlation between mRNA levels and protein abundances is moderate in most studies, occasionally attributed to complex post-transcriptional regulation. To address this, we generated a paired transcriptome/proteome time course dataset with 14 time poin...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2018-10-26 | PXD011238 | Pride
The microarrays experiments of three biological and one technical replicates were performed in YJR12 (wt) and YJR13 (myo1?) strains. YJR12 (wild type) and YJR13 (myo1?) strains were obtained as haploid segregants from a cross between YJR6 (myo1::HIS5 strain) and BY4741 (obtained from ATTC). Cultures...
ORGANISM(S): Saccharomyces cerevisiae 
Higher plants encode four or five DICER-LIKE (DCL) enzymes responsible for the production of small non-coding RNAs which function in RNA interference (RNAi). Different RNAi pathways in plants effect transposon silencing, antiviral defense and endogenous gene regulation. DCL2 acts genetically redunda...
ORGANISM(S): Arabidopsis Thaliana 
Post-transcriptional regulation of Ribosome Biogenesis during differentiation [dRNA-seq]
Post-transcriptional regulation of proliferation and quiescence (mRNAdecay)
Post-transcriptional regulation of Ribosome Biogenesis during differentiation [SLAM-seq]
Post-transcriptional regulation of proliferation and quiescence
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