Sort   by:  
 Page size 
ProteomicsDimeric IgA specifically disables intracellular mutated oncodrivers
Despite their long half-life, therapeutic antibodies are considered ineffective against intracellular antigens due to their perceived inability to penetrate epithelial cells. Using recombinant antibodies targeting common mutations in oncogenes, we show that dimeric IgA, but not the same antibody on ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD042914 | Pride
Transcytosis Cancer Therapeutic antibodies Immunoglobulin a 
ProteomicsDimeric IgA specifically disables intracellular mutated oncodrivers
Despite their long half-life, therapeutic antibodies are considered ineffective against intracellular antigens due to their perceived inability to penetrate epithelial cells. Using recombinant antibodies targeting common mutations in oncogenes, we demonstrate that dimeric IgA, but not the same antib...
ORGANISM(S): Homo Sapiens 
2026-06-12 | PXD044426 | panorama
UnknownTreatments Administered to the First 9152 Reported Cases of COVID-19: A Systematic Review.
Not available
S-EPMC7251321 | biostudies-literature
ProteomicsRdRp MALDI Data Set - 2022, Slavish/Rimmer
Chemical scaffold recycling: Structure-guided conversion of an HIV integrase inhibitor into a potent influenza virus RNA-dependent RNA polymerase inhibitor designed to minimize resistance potential Eur J Med Chem. 2023 Feb 5;247:115035. doi: 10.1016/j.ejmech.2022.115035. Epub 2022 Dec 22. Slavish, ...
ORGANISM(S): Influenza Virus A/california/04/2009 
2023-07-06 | MSV000092363 | MassIVE
UnknownPolygenic risk score association with multiple sclerosis susceptibility and phenotype in Europeans.
Not available
S-EPMC10169285 | biostudies-literature
GenomicsGenome wide association study on coronary heart disease in patients with familial hypercholesterolemia
Mutations in the low-density lipoprotein receptor (LDLR) gene cause familial hypercholesterolemia (FH), a disorder characterized by coronary heart disease (CHD) at young age. We aimed to apply an extreme sampling method to enhance the statistical power to identify novel genetic risk variants for CHD...
EGAS00001000734 | EGA
UnknownViral resuppression and detection of drug resistance following interruption of a suppressive non-nucleoside reverse transcriptase inhibitor-based regimen.
Not available
S-EPMC2745911 | biostudies-literature
UnknownFactors associated with D-dimer levels in HIV-infected individuals.
Not available
S-EPMC3953205 | biostudies-literature
UnknownEffects of combination lipid therapy in type 2 diabetes mellitus.
Not available
S-EPMC2879499 | biostudies-literature
UnknownEffects of intensive blood-pressure control in type 2 diabetes mellitus.
Not available
S-EPMC4123215 | biostudies-literature
Sort   by:  
 Page size