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ProteomicsIntracellular proteins adsorbed on AuNPs during transcytosis and exocytosis
we set protein corona as the research object in this study, and focused on exploring the biological effects of intracellular protein corona (IPC) that formed on particle surface after transcytosis of nanomedicines. Considering the multi-functionalization characteristic, gold nanoparticles (AuNPs) we...
ORGANISM(S): Homo sapiens (Human) 
2020-01-20 | PXD015651 | Pride
Transcytosis Exocytosis Protein corona Caco-2 Aunps 
ProteomicsIgA transcytosis and tumor antigen recognition govern anti-tumor immunity in ovarian cancer
Although most ovarian cancers show prognostically relevant activated T-cell infiltrates, response rates to immune checkpoint inhibitors are very modest4. Memory B-cell and plasma cell infiltrates have been associated with better outcome in ovarian cancer, but the nature and functional relevance of t...
ORGANISM(S): Homo sapiens (Human) 
2020-12-01 | PXD018079 | Pride
Ovarian cancer Prm Immunoglobulin a Transcytosis Lc-ms/ms Immunotherapy 
GenomicsMonocytes release pro-cathepsin D to drive blood-to-brain transcytosis in diabetes
Monocytes release pro-cathepsin D to drive blood-to-brain transcytosis in diabetes
PRJNA1065906 | ENA
ProteomicsPathogenic Bacteria Exploit Transferrin Receptor Transcytosis to Penetrate the Blood‒Brain Barrier
In this study, we present evidence showing that the infection with the major meningitis-causing bacteria, NMEC, GBS and SPN, activates the same fusion process of bacteria-containing vesicles (BCVs) with TfR vesicles, which enables those bacteria to exploit TfR transcytosis to penetrate the BBB, and ...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD039060 | Pride
Lc-ms Hbmec Human 
TranscriptomicsMonocytes release pro-cathepsin D to drive blood-to-brain transcytosis in diabetes
Microvascular complications are the major outcome of type 2 diabetes mellitus progression and the underlying mechanism remains to be determined. To explore the contribution of circulating monocytes to the microvascular lesions, high-throughput RNA sequencing was conducted and we found high-level exp...
ORGANISM(S): Homo sapiens 
2024-01-23 | GSE253502 | GEO
UnknownUnraveling GLUT-mediated transcytosis pathway of glycosylated nanodisks.
Not available
S-EPMC7878461 | biostudies-literature
UnknownGradual Suppression of Transcytosis Governs Functional Blood-Retinal Barrier Formation.
Not available
S-EPMC5480403 | biostudies-literature
UnknownSecretion of L-glutamate from osteoclasts through transcytosis.
Not available
S-EPMC1570443 | biostudies-literature
UnknownApplication of In vitro transcytosis models to brain targeted biologics.
Not available
S-EPMC10446226 | biostudies-literature
UnknownSuppression of transcytosis regulates zebrafish blood-brain barrier function.
Not available
S-EPMC6726461 | biostudies-literature
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