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MetabolomicsHigh-Precision Automated Workflow for Urinary Untargeted Metabolomic Epidemiology
Urine is a non-invasive biofluid that is rich in polar metabolites and well-suited for metabolomic epidemiology. However, due to individual variability in health and hydration status, the physiological concentration of urine can differ >15-fold, which can pose major challenges in untargeted LC-MS me...
2021-06-10 | MTBLS2295 | MetaboLights
MetabolomicsInvestigation of cross-platform analytical precision in NMR and UPLC-MS based metabolic-phenotyping
Dataset of six samples of pooled human urine, aliquoted, and independently prepared and aquired by NMR spectroscopy, and UPLC-MS. Each source sample is seperatly prepared and assayed thirteen times. A pooled QC sample and independent external reference of a compariable matrix is also aquired to assi...
2018-08-31 | MTBLS694 | MetaboLights
MetabolomicsDigital Phenomics and Dual-Fluid Metabolomics for Precision Stratification of Diabetic Kidney Disease: A Multicenter Cohort Study

We conducted a prospective-retrospective two-center cohort study involving 364 participants. The Discovery Cohort (n=282) enrolled from two centers consisted of healthy controls (n=80), patients with type 2 diabetes mellitus (T2DM) without kidney disease (n=102), and patients with confirmed DKD (...

2026-03-09 | MTBLS14007 | MetaboLights
GenomicVA APOLLO Project - Research for Precision Oncology (RePOP)

The Research for Precision Oncology Program (RePOP) is a research activity that establishes a cohort of Veterans diagnosed with cancer and who have had genomic analyses performed on their tumor tissue as part of standard of care. All data relevant to a patient's cancer and cancer care will be...

phs001374 | dbGaP
TranscriptomicsIntratumor Heterogeneity and Precision of Microarray-Based Predictors of Breast Cancer Biology and Clinical Outcome
Genome-wide expression profiling was performed on 50 core needle biopsies from 18 breast cancer patients using Affymetrix GeneChip Human Genome Plus 2.0 Arrays. Global profiles of expression were characterized using unsupervised clustering methods and variance components models. Precision of predict...
ORGANISM(S): Homo sapiens 
2010-08-12 | E-GEOD-23593 | biostudies-arrayexpress
TranscriptomicsUsing a rhabdomyosarcoma patient-derived xenograft to examine precision medicine approaches and model acquired resistance.
Original patient tumor is directly implanted in mice xenografts. Tumor is propagated to multiple mice for conduct of 6 arm treatment trials and control. Therapies are selected based on T0 and F0 genomic profiles. ICE-T refractory tumor are implanted and additional 6 arm treatment trial and control c...
ORGANISM(S): Homo sapiens 
2014-07-22 | E-GEOD-51130 | biostudies-arrayexpress
ProteomicsPrecision N-glycoproteomics of murine peritoneal macrophage
In this study, we profiled the precision N-glycoproteome of the murine peritoneal macrophage under different stimulation.
ORGANISM(S): Mus musculus (Mouse) 
2021-06-12 | PXD026629 | Pride
Inflammation Glycoproteomics Macrophage 
ProteomicsClinical-proteomic classification and precision treatment strategy of chordoma
Clinical-proteomic classification and precision treatment strategy of chordoma
ORGANISM(S): Homo Sapiens 
2024-07-04 | PXD053631 |
ProteomicsOvercoming the detrimental O-acylation in TMTpro labeling improves the proteome depth and quantification precision.
The advent of TMTpro reagents expands the sample multiplexing capacity and enables quantification of up to 18 samples in a multiplexed manner. Similar to classic TMT reagents, TMTpro reagents contain a tertiary amine group in their mole-cules, which markedly enhances their reactivity toward hydroxyl...
ORGANISM(S): Homo Sapiens Saccharomyces Cerevisiae 
2023-12-19 | PXD043778 |
UnknownCharacterization of cancer genomic heterogeneity by next-generation sequencing advances precision medicine in cancer treatment.
Not available
S-EPMC6333046 | biostudies-literature
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