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ProteomicsMisincorporations at Artificially Constructed Termination Stop Codons in the Presence of the Amino Glycoside Gentamicin
Readthrough of a translation termination codon is regulated by ribosomal A site recognition and insertion of near-cognate tRNAs. Small molecules exist that mediate the incorporation of amino acids at the stop codon and the production of full-length, often functional protein but defining the actual a...
ORGANISM(S): Homo sapiens (Human) 
2024-10-29 | PXD039307 | Pride
Lc-msms Cancer Aminoglycoside P53 protein Premature stop codon 
ProteomicsEnvironment Modulates Protein Heterogeneity Through Transcriptional and Translational Stop Codon Recoding
Stop codon recoding events give rise to longer proteins, which may alter the proteins function and thereby generate short-lasting phenotypic variability from a single gene. In order to systematically assess the frequency and origin of recoding events, we designed a library of reporters. We introduce...
ORGANISM(S): Escherichia Coli (ncbitaxon:562) 
2023-01-14 | MSV000091065 | MassIVE
GenomicsENVIRONMENT MODULATES PROTEIN HETEROGENEITY THROUGH TRANSCRIPTIONAL AND TRANSLATIONAL STOP CODON RECODING
ENVIRONMENT MODULATES PROTEIN HETEROGENEITY THROUGH TRANSCRIPTIONAL AND TRANSLATIONAL STOP CODON RECODING
PRJNA942285 | ENA
GenomicsStop Codon Context Influences Genome-Wide Stimulation of Termination Codon Readthrough by Aminoglycosides [Dataset 4]
Stop Codon Context Influences Genome-Wide Stimulation of Termination Codon Readthrough by Aminoglycosides [Dataset 4]
PRJNA576652 | ENA
GenomicsStop Codon Context Influences Genome-Wide Stimulation of Termination Codon Readthrough by Aminoglycosides [Dataset 2]
Stop Codon Context Influences Genome-Wide Stimulation of Termination Codon Readthrough by Aminoglycosides [Dataset 2]
PRJNA576650 | ENA
GenomicsStop Codon Context Influences Genome-Wide Stimulation of Termination Codon Readthrough by Aminoglycosides [Dataset 3]
Stop Codon Context Influences Genome-Wide Stimulation of Termination Codon Readthrough by Aminoglycosides [Dataset 3]
PRJNA576651 | ENA
GenomicsStop Codon Context Influences Genome-Wide Stimulation of Termination Codon Readthrough by Aminoglycosides [Dataset 5]
Stop Codon Context Influences Genome-Wide Stimulation of Termination Codon Readthrough by Aminoglycosides [Dataset 5]
PRJNA576653 | ENA
GenomicsStop Codon Context Influences Genome-Wide Stimulation of Termination Codon Readthrough by Aminoglycosides [Dataset 1]
Stop Codon Context Influences Genome-Wide Stimulation of Termination Codon Readthrough by Aminoglycosides [Dataset 1]
PRJNA576649 | ENA
OtherENVIRONMENT MODULATES PROTEIN HETEROGENEITY THROUGH TRANSCRIPTIONAL AND TRANSLATIONAL STOP CODON RECODING
In order to systematically assess the frequency and origin of stop codon recoding events, we designed a library of reporters. We introduced premature stop codons into mScarlet that enabled high-throughput quantification of protein synthesis termination errors in E. coli using fluorescent microscopy....
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2024-03-28 | GSE226936 | GEO
GenomicsStop codon recoding is widespread in diverse phage lineages and has the potential to regulate translation of late stage and lytic genes
Stop codon recoding in bacteriophages
PRJEB51122 | ENA
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