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MetabolomicsPrenatal exposure to trace elements impacts mother-infant gut microbiome, metabolome and resistome during the first year of life

Infancy is a critical period for the colonization of the gut microbiome. However, xenobiotic effects on gut microbiome development in early life remain poorly understood. Here, we recruit 146 mother-infant pairs and collect stool samples at 3, 6, and 12 months after delivery for amplicon sequenci...

2025-05-02 | MTBLS11392 | MetaboLights
MetabolomicsPrenatal exposures and Metabolite and Lipid Profiles
Not available
ORGANISM(S): Homo sapiens 
ST000523 | MetabolomicsWorkbench
MetabolomicsMetabolomic and Transcriptomic Signatures of Prenatal Excessive Methionine in Mice
Not available
ORGANISM(S): Mus musculus 
ST001413 | MetabolomicsWorkbench
TranscriptomicsSex-specific effects of prenatal stress in 5-Htt deficient mice: towards molecular mechanisms of gene x environment interactions
prenatal stress response, genetic modification Background: Prenatal stress (PS) exposure has been shown to increase the risk for emotional disorders in later life. Furthermore, the serotonin transporter (5-HTT) genotype is suggested to exert a modulating effect on the association between early life ...
ORGANISM(S): Mus musculus 
2011-12-12 | E-GEOD-26025 | biostudies-arrayexpress
GenomicsNoninvasive prenatal molecular karyotyping from maternal plasma
Fetal DNA is present in the plasma of pregnant women. Massively parallel sequencing of maternal plasma DNA has been used to detect fetal trisomies 21, 18, 13 and selected sex chromosomal aneuploidies noninvasively. Case reports describing the detection of fetal microdeletions from maternal plasma...
EGAS00001000439 | EGA
Transcriptomicsuse of aCGH in a large series of prenatal samples
we have conducted a comparative study of the different technologies available for the detection of chromosomal abnormalities in prenatal samples. Here we include results of the aCGH experiments this series is composed of internal controls plus a year-long (2009-2010) consecutive series of pregnant w...
ORGANISM(S): Homo sapiens 
2014-01-07 | E-GEOD-26654 | biostudies-arrayexpress
ProteomicsNeurodevelopmental Impact of Prenatal Stress: A Proteomic Analysis of Myelination Disruptions in the Avian Embryo
Prenatal stress induced by maternal activation of the hypothalamic-pituitary-adrenal (HPA) axis and subsequent release of glucocorticoids can profoundly affect fetal brain development. This study investigates the molecular mechanisms underlying prenatal stress in Gallus gallus domesticus by analyzin...
ORGANISM(S): Gallus gallus (Chicken) 
2025-10-27 | PXD055206 | Pride
Gallus gallus domesticus Proteomics Myelin Prenatal stress Corticosterone 
UnknownPrenatal Recurrence of Ductal Plate Malformations Leads to PKHD1 Variant Reclassification.
Not available
S-EPMC12611536 | biostudies-literature
UnknownEvolving Practices in Prenatal Open Spinal Dysraphism: A Global Survey of Selection Criteria, Surgical Techniques, and Diagnostic Trends.
Not available
S-EPMC12819936 | biostudies-literature
TranscriptomicsDNA methylation signatures triggered by prenatal maternal stress exposure to a natural disaster: Project Ice Storm
Background: Prenatal maternal stress (PNMS) predicts a wide variety of behavioral and physical outcomes in the offspring. Although epigenetic processes may be responsible for PNMS effects, human research is hampered by the lack of experimental methods that parallel controlled animal studies. Disaste...
ORGANISM(S): Homo sapiens 
2015-08-26 | E-GEOD-72354 | biostudies-arrayexpress
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