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UnknownPrediction of prkC-mediated protein serine/threonine phosphorylation sites for bacteria.
Not available
S-EPMC6168130 | biostudies-literature
ProteomicsThe Serine/Threonine kinase PrkC of Clostridioides difficile regulates export of CD1135, a septal peptidoglycan hydrolase
Cell growth and division require a balance between synthesis and hydrolysis of the peptidoglycan (PG). Inhibition of PG synthesis or uncontrolled PG hydrolysis can be lethal for the cells, making it imperative to control peptidoglycan hydrolase (PGH) activity. The activity of several enzymes involv...
ORGANISM(S): Peptoclostridium difficile (strain 630) (Clostridium difficile) 
2021-04-08 | PXD021541 | Pride
Phosphoproteomics Clostridium difficile Qexactive plus Phostag 
ProteomicsThe role of the Ser/Thr kinase PrkC of Clostridium difficile in cell wall homeostasis and antimicrobial resistance.
Clostridium difficile is the leading cause of antibiotic associated diarrhea in adults. During infection, the bacteria must rapidly respond and adapt to the host environment by being able to activate survival strategies. Ser/Thr kinases (STKs) are involved in signal transduction and regulate numerou...
ORGANISM(S): Clostridioides difficile 
2019-06-14 | PXD012241 | Pride
Qexactive hf Clostridium difficile Cell wall Shotgun proteomics 
UnknownThe Par-PrkC polarity complex is required for cilia growth in zebrafish photoreceptors.
Not available
S-EPMC4140697 | biostudies-literature
UnknownThe stability of cytadherence proteins in Mycoplasma pneumoniae requires activity of the protein kinase PrkC.
Not available
S-EPMC2798226 | biostudies-literature
UnknownDual regulation of activity and intracellular localization of the PASTA kinase PrkC during Bacillus subtilis growth.
Not available
S-EPMC5786024 | biostudies-literature
ProteomicsThe cellular and proteomic response of primary and immortalized murine Kupffer cells following immune stimulation diverges from that of monocyte-derived macrophages
Kupffer cells are the first line of defense in the liver against pathogens, yet several microbes successfully target the liver, bypass immune surveillance, and effectively develop in this tissue. Our current, albeit poor, understanding of Kupffer cell-pathogen interactions has been largely achieved ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-22 | MSV000079995 | MassIVE
GenomicsBacillus subtilis subsp. subtilis
Whole Genome Sequencing of a knockout reporter strain targeting gene prkC for publication
PRJNA1440371 | ENA
UnknownBacillus anthracis chain length, a virulence determinant, is regulated by membrane localized serine/threonine protein kinase PrkC.
Not available
S-EPMC8117516 | biostudies-literature
UnknownSer/Thr protein kinase PrkC-mediated regulation of GroEL is critical for biofilm formation in Bacillus anthracis.
Not available
S-EPMC5460178 | biostudies-literature
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