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Mutations in leucine rich repeat kinase 2 (LRRK2) are a common cause of inherited and sporadic Parkinson’s disease (PD) and previous work suggests that dephosphorylation of LRRK2 at a cluster of heterologous phosphosites is associated to disease. We have previously reported subunits of the PP1 and P...
ORGANISM(S): Homo sapiens (Human) 
2023-12-06 | PXD044933 | Pride
Cell growth and division require a balance between synthesis and hydrolysis of the peptidoglycan (PG). Inhibition of PG synthesis or uncontrolled PG hydrolysis can be lethal for the cells, making it imperative to control peptidoglycan hydrolase (PGH) activity. The activity of several enzymes involv...
ORGANISM(S): Peptoclostridium difficile (strain 630) (Clostridium difficile) 
2021-04-08 | PXD021541 | Pride
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