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TranscriptomicsEarly-induced genes of human regulatory CD4+CD25hi Treg and CD4+CD25- Th cells
Goals and objectives of this study: to identify genes preferentially induced in human CD4+CD25hi Treg cells following T-cell activation with potential role for stabililization & maintenance of the regulatory program. Keywords: T-cell receptor stimulation, gene-regulation, comparative gene expressio...
ORGANISM(S): Homo sapiens 
2009-04-20 | E-GEOD-13017 | biostudies-arrayexpress
TranscriptomicsHuman activated Treg cells and retrovirally engineered Th cells, transduced with GARP, FOXP3 or control GFP vector
Goals and objectives of this study: to identify genes of the Treg signature induced by consitutive expression of GARP or FOXP3 in antigen-specific Th cells with potential role for stabililization & maintenance of the regulatory program. Keywords: T-cell receptor stimulation, gene-regulation, compar...
ORGANISM(S): Homo sapiens 
2009-04-20 | E-GEOD-13234 | biostudies-arrayexpress
TranscriptomicsHigh-time-resolution dynamic analysis of human regulatory T cell (Treg) / CD4+ T-effector cell (Teff) activation
Human FOXP3+CD25+CD4+ regulatory T cells (Tregs) play a dominant role in the maintenance of immune homeostasis. Several genes are known to be important for murine Tregs, but for human Tregs the genes and underlying molecular networks controlling the suppressor function still largely remain unclear. ...
ORGANISM(S): Homo sapiens 
2012-11-23 | E-GEOD-11292 | biostudies-arrayexpress
UnknownPerspectives on Regulatory T Cell Therapies.
Not available
S-EPMC2969127 | biostudies-literature
TranscriptomicsTranscription profiling of human regulatory T cells to identify genes under Foxp3 control
Foxp3, a transcription factor of the forkhead/winged helix family, plays a unique role in the transcriptional control of regulatory CD4+CD25+ T (Treg) cells. The identification of potential target genes associated with the regulatory phenotype and the characterization of combinatorial interactions o...
ORGANISM(S): Homo sapiens 
2005-01-24 | E-MEXP-228 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of macrophages derived from WT and Vdr dificient mice after stimulation with IFNgamma and/or 1alpha,25(OH)2D3 to study molecular mechanisms of macrophage activation
Gene expression profiling of macrophages derived from WT and Vdr deficient mice after stimulation with IFNgamma and/or 1alpha,25(OH)2D3
ORGANISM(S): Mus musculus 
2007-08-31 | E-GEOD-2421 | biostudies-arrayexpress
UnknownPLAU inferred from a correlation network is critical for suppressor function of regulatory T cells.
Not available
S-EPMC3531908 | biostudies-literature
UnknownIdentification of novel regulators in T-cell differentiation of aplastic anemia patients.
Not available
S-EPMC1626471 | biostudies-literature
UnknownSignatures of human regulatory T cells: an encounter with old friends and new players.
Not available
S-EPMC1779567 | biostudies-literature
TranscriptomicsTranscription profiling of mouse Foxp3- CD25- regulatory T cells
The concept of immune regulation/suppression has been well-established. With thymus-derived CD4 CD25 regulatory T (TR) cells, it became clear that a variety of additional peripherally induced TR cells play vital roles in protection from many harmful immune responses including intestinal inflammatio...
ORGANISM(S): Mus musculus 
2008-10-25 | E-GEOD-12506 | biostudies-arrayexpress
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