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Neutralization of truncated procalcitonin by antibody treatment protects vascular barrier integrity during systemic inflammation
Background: Distinguishing between bacterial and viral lower respiratory tract infections (LRTI) in hospitalized patients remains challenging. Transcriptional profiling is a promising tool for improving diagnosis in LRTI. Methods: We performed whole blood transcriptional analysis in a cohort of ...
ORGANISM(S): Homo sapiens 
Differentially expressed genes were identified in lung endothelial cells of CLP-treated mice compared to sham-treated controls and after treatment with an antibody against truncated murine procalcitonin.
ORGANISM(S): Mus musculus 
2024-07-22 | GSE245013 | GEO
PCT concentration in the bloodstream correlates well with sepsis presence and in severe cases increases up to a thousand times from the healthy physiological values in a short time. In this study, we developed a rapid technique for PCT detection by MALDI-MS, that uses in-situ enrichment directly on ...
ORGANISM(S): Homo sapiens (Human) 
2023-07-20 | PXD035456 | Pride
Characterization of recombinant procalcitonin used as a standard for quantification.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-05-23 | MSV000092010 | MassIVE
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