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ProteomicsThe Parkinson's disease protein alpha-synuclein is a direct modulator of Processing-bodies and mRNA stability
Hallacli E, Kayatekin C, Nazeen S, Wang XH, Sheinkopf Z, Sathyakumar S, Sarkar S, Jiang X, Dong X, Di Maio R, Wang W, Keeney MT, Felsky D, Sandoe J, Vahdatshoar A, Udeshi ND, Mani DR,Carr SA, de Jager P, Myers CL, Lindquist S, Greenmyre TJ, Bartel DP, Feany MB, Sunyaev S, Chung CY and Khurana V. Alp...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-03-09 | MSV000089026 | MassIVE
TranscriptomicsShort-term (12h) ATRA treatment of embryoid bodies.
We used microarrays to detail the global programme of gene expression in embryonic stem cells, early differentiated embrioid bodies and effect of short-term ATRA treatment. Expression data from undifferentiated mouse embryonic stem cells (D3), four-day old aggregated embrioid bodies and 12h atRA or ...
ORGANISM(S): Mus musculus 
2010-07-16 | E-GEOD-20919 | biostudies-arrayexpress
TranscriptomicsLMKB/MARF1 localizes to mRNA processing bodies, interacts with Ge-1, and regulates IFI44L gene expression
The mRNA processing body is a cellular structure that regulates the stability of cytoplasmic mRNA. MARF1/LMKB is an RNA-binding protein that is associated with maintenance of mRNA homeostasis and genomic stability. To investigate the function of LMKB in a human B lymphocyte cell line, BJAB cells w...
ORGANISM(S): Homo sapiens 
2014-06-09 | E-GEOD-55974 | biostudies-arrayexpress
ProteomicsThe proteome of Processing Bodies in Arabidopsis.
An Affinity Purification (AP) step coupled with Proximity-dependent biotin ligation (PDL) reveals the proteome of Processing Bodies (PBs) in Arabidopsis.
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2023-01-17 | PXD037701 | Pride
Arabidopsis Lc-ms/ms Processing bodies Proteome 
GenomicsProcessing Bodies Restrict the Specification of Human Primordial Germ Cells
Processing Bodies Restrict the Specification of Human Primordial Germ Cells
PRJNA1212043 | ENA
TranscriptomicsExpression data from 0.15M and 0.7M-fed wild-type and ChREBP mutant, third instar Drosophila larval fat bodies (FBs)
Chronic high sugar feeding induces obesity, hyperglycemia, and insulin resistance in flies and mammals. These phenotypes are controlled by the fat body, a liver- and adipose- like tissue in Drosophila flies. To gain insight into the mechanisms underlying the connection between diet and insulin sensi...
ORGANISM(S): Drosophila melanogaster 
2013-01-25 | E-GEOD-43734 | biostudies-arrayexpress
GenomicsP-bodies act as sites for dynamic RNA processing
P-bodies act as sites for dynamic RNA processing
PRJNA1374136 | ENA
ProteomicsProteome Profiling of PBMC-originated, iPSC-derived Lentoid Bodies at differentiation day 35
Differentiation of pluripotent stem cells into lentoid bodies is important for the understanding of the lens development and investigating the processes critical for lens morphogenesis. This Study was initiated to investigate a comprehensive proteome profiling of the peripheral blood mononuclear cel...
ORGANISM(S): Homo sapiens (Human) 
2022-02-28 | PXD009633 | Pride
Mass-spectrometry Ipsc-derived lentoid bodies Proteome Pbmc 
GenomicsRNA Decay in Processing Bodies is Indispensable for Adipogenesis
RNA Decay in Processing Bodies is Indispensable for Adipogenesis
PRJNA700985 | ENA
TranscriptomicsHITS-CLIP analysis of Yb binding sites in Drosophila ovary cell line
piRNAs direct Piwi to repress transposons to maintain genome integrity in Drosophila ovarian somatic cells. piRNA maturation and association with Piwi occur at perinuclear Yb bodies, the centers of piRNA biogenesis. Here, we show that piRNA intermediates arising from the piRNA cluster flamenco (flam...
ORGANISM(S): Drosophila melanogaster 
2014-06-24 | E-GEOD-54875 | biostudies-arrayexpress
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