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ProteomicsIdentification of a precursor processing protease from the spider Cupiennius salei essential for venom neurotoxin maturation
Spider venom neurotoxins and cytolytic peptides are expressed as elongated precursor peptides, which are post-translationally processed by proteases to yield the active mature peptides. The recognition motifs for these processing proteases, first published more than ten years ago, include the Proces...
ORGANISM(S): Cupiennius salei (American wandering spider) 
2018-01-02 | PXD007126 | Pride
Ipqm Neurotoxin Pqm Propeptide Venom Cupiennius salei Processing quadruplet motif Protease Enzyme purification 
UnknownIdentification of a precursor processing protease from the spider Cupiennius salei essential for venom neurotoxin maturation.
Not available
S-EPMC5808768 | biostudies-literature
TranscriptomicsPedigreed Primate Embryonic Stem Cells Express Homogeneous Familial Gene Profiles
Pedigreed primate ESCs display homogeneous and reliable expression profiles. These similarities to mouse ESCs suggest that heterogeneities found among hESCs result from their disparate origins rather than intrinsic biological limitations with primate embryonic stem cells. Keywords: different nhpESC ...
ORGANISM(S): Macaca mulatta 
2008-04-14 | E-GEOD-7534 | biostudies-arrayexpress
ProteomicseIF4A1 unwinding activity is RNA sequence-specifically deployed through eIF4A1-multimerisation to facilitate translation of mRNAs with local repressive RNA structure
Oncogenic translational programmes are an emerging hallmark of cancer and often driven by dysregulation of signaling pathways including KRAS and mTORC that converge on the eukaryotic translation initiation (eIF) 4F complex. Altered eIF4F activity promotes translation of oncogene mRNAs that typically...
ORGANISM(S): Homo sapiens (Human) 
2023-01-17 | PXD034343 | Pride
Proteomics Tmt Eif4a1 Pulse silac 
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