Sort   by:  
 Page size 
GenomicsInhibition of mitochondrial transcription by the neurotoxin MPP+
Inhibition of mitochondrial transcription by the neurotoxin MPP+
PRJNA884437 | ENA
ProteomicsIdentification of a precursor processing protease from the spider Cupiennius salei essential for venom neurotoxin maturation
Spider venom neurotoxins and cytolytic peptides are expressed as elongated precursor peptides, which are post-translationally processed by proteases to yield the active mature peptides. The recognition motifs for these processing proteases, first published more than ten years ago, include the Proces...
ORGANISM(S): Cupiennius salei (American wandering spider) 
2018-01-02 | PXD007126 | Pride
Ipqm Neurotoxin Pqm Propeptide Venom Cupiennius salei Processing quadruplet motif Protease Enzyme purification 
ProteomicsSynaptosome proteomics of tetanus neurotoxin-injected mice
Network hyperexcitability is manifested as frequent ictal discharges, often caused by unbalanced neurotransmission. We assessed synaptic changes in the hyperexcitable visual cortex of tetanus neurotoxin-injected mice (TeNT). A proteomics analysis of synaptic content revealed Carboxypeptidase E (CPE)...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-09 | PXD022270 | Pride
Tetanus neurotoxin Tmt Epilepsy Synaptosome 
UnknownPlasma membrane localization signals in the light chain of botulinum neurotoxin.
Not available
S-EPMC365768 | biostudies-literature
TranscriptomicsInhibition of mitochondrial transcription by the neurotoxin MPP+
The neurotoxin MPP+ triggers cell death of dopamine neurons and induces Parkinson’s disease symptoms in mice and men, but the immediate transcriptional response to this neurotoxin has not been studied. We therefore treated human SH-SY5Y cells with a low dose (0.1 mM) of MPP+ and measured the effect ...
ORGANISM(S): Homo sapiens 
2023-06-01 | GSE214243 | GEO
TranscriptomicsBotulinum neurotoxin A induced expression profiles in Raw264.7 cells
Botulinum neurotoxin type A (BoNT/A) is one of the most potent protein toxins, which makes it a possible biological weapon and therapeutic. Using microarray analysis we performed global transcriptional profiling of RAW264.7 cells, a murine alveolar macrophage cell line. Time dependent expression pro...
ORGANISM(S): Mus musculus 
2014-12-20 | E-GEOD-64390 | biostudies-arrayexpress
UnknownCharacterization of clostridium botulinum neurotoxin serotype A (BoNT/A) and fibroblast growth factor receptor interactions using novel receptor dimerization assay.
Not available
S-EPMC8035261 | biostudies-literature
GenomicsGene expression profiling in human nasal epithelial cells (HNEpCs) stimulated with eosinophil-derived neurotoxin (EDN)
Gene expression profiling in human nasal epithelial cells (HNEpCs) stimulated with eosinophil-derived neurotoxin (EDN)
PRJNA437627 | ENA
UnknownBotulinum Neurotoxin Type A Directly Affects Sebocytes and Modulates Oleic Acid-Induced Lipogenesis.
Not available
S-EPMC9609209 | biostudies-literature
TranscriptomicsTranscription profiling of mouse models or Parkinsons disease reveal miRNAs and codon usage regulate striatal gene and protein expression
The molecular mechanisms underlying the changes in the nigrostriatal pathway in Parkinson’s disease (PD) are not completely understood. Here we use microarrays and mass spectrometry to study the transcriptomic and proteomic changes in the striatum of two mouse models of PD induced by distinct neu...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-8030 | biostudies-arrayexpress
Sort   by:  
 Page size