Epilepsy - OmicsDI

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Tissue

Brain (47)
Brain (7)
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Fibroblast (4)
Cell culture (4)
Cerebrospinal fluid (3)
Neuron (2)
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Disease

Normal (24)
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Benign adult familial myoclonic epilepsy (1)
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Ewing family tumor (1)
Insulitis and diabetes (1)
Early-life seizures (1)
Aggressive insulitis (1)
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Oropharynx squamous-cell carcinoma in DiseaseLocation oropharynx has DiseaseStaging lymph node negative (N0) (1)
T. circumcincta infection (1)
Serratia marcesens infected (1)
Myeloid neoplasm (1)
Cryptozoospermia (1)
Embryonic lethal at day 8.5 to 9.5 (1)
Infected with IBDV strain F52/70 (1)
Postnatal day 18 was the earliest time point at which structural differences between testes from wild-type and pcd3J-/- mice were observed via histopathology. (1)

Technology Type

Mass Spectrometry (81)
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ESI (3)
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KINOMEscan (2)
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HiSeq X Ten, ILLUMINA (1)
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Instrument Platform

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Scanning of was performed on an Axon 4000B scanner (2)
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UNIPROT ID/AC

SERF1_HUMAN (1)
ZN696_HUMAN (1)
CX6B2_HUMAN (1)
FGF11_HUMAN (1)
CRX_HUMAN (1)
ZN195_HUMAN (1)
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FCRL4_HUMAN (1)
B2L12_HUMAN (1)
GPT2L_HUMAN (1)
NPFF2_HUMAN (1)
ZN713_HUMAN (1)

ENSEMBL ID

ENSG00000170477 (6)

CHEBI ID

CHEBI:30769 (8)
CHEBI:16704 (8)
CHEBI:16414 (7)
CHEBI:16335 (7)
CHEBI:16919 (7)
CHEBI:17191 (6)
CHEBI:16857 (6)
CHEBI:16196 (6)
CHEBI:17895 (6)
CHEBI:16828 (6)
CHEBI:18089 (6)
CHEBI:16566 (6)
CHEBI:18019 (6)
CHEBI:15971 (6)
CHEBI:16015 (6)
CHEBI:15891 (6)
CHEBI:32816 (6)
CHEBI:30915 (6)
CHEBI:83053 (5)
CHEBI:24813 (5)
CHEBI:30805 (5)
CHEBI:32365 (5)
CHEBI:17115 (5)
CHEBI:18050 (5)
CHEBI:17295 (5)
CHEBI:17196 (5)
CHEBI:16467 (5)
CHEBI:16977 (5)
CHEBI:17351 (5)
CHEBI:16393 (5)

Metabolite Name

Glycerophosphocholine (12)
Uracil (12)
Creatine (12)
Adenosine (10)
Creatinine (10)
Betaine (9)
Sphingosine (9)
Cholic acid (8)
Hypoxanthine (8)
Choline (8)
Phytosphingosine (7)
Indole (7)
Sphinganine (7)
Spermidine (7)
Adenine (7)
L-Histidine (7)
Taurine (7)
Uridine (7)
PC(16:0/16:0) (6)
Spermine (6)
Hydrocortisone (6)
Serotonin (6)
Biliverdin (6)
Acetylcarnitine (6)
4-Hydroxybenzaldehyde (6)
Deoxycholic acid (6)
Glycocholic acid (6)
Oleamide (6)
Tyrosine (6)
Sarcosine (6)

First Public Date

2024 (106)
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2025 (97)
2014 (90)
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2020 (47)
2019 (38)
2021 (35)
2017 (27)
2016 (26)
2018 (24)
2015 (16)
2013 (15)

Modelling Approach

Ordinary differential equation model (1)

Study status

Recruiting (4)
Not yet recruiting (3)
Terminated (1)
Completed (1)

Lab affiliation

Head of Proteomics (4)
National Key Laboratory of Medical Molecular Biology & Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, 5 Dong Dan San Tiao, Dongcheng District, Beijing 100005, China. (2)
Proteomics & Metabolomics Facility, University of Connecticut (2)
Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania "Luigi Vanvitelli", Caserta, Italy (2)
Developmental Neurobiology, Max Planck Institute of Psychiatry, Munich, Germany (1)
University of Nebraska, Lincoln (1)
Max-Planck-Institute for Multidisciplinary Sciences Bioanalytical Mass Spectrometry Group Am Fassberg 11 D-37077 Goettingen Germany (1)
University of Southern Denmark, Department og Biochemistry and Molecular Biology (1)
Shanghai Institute of Materia Medica, Chinese Academy of Sciences. (1)
Department of Chemistry, Imperial College London, Molecular Research Science Hub, 80 Wood Lane, London W12 0BZ, United Kingdom. The Francis Crick Institute, 1 Midland Road, London NW1 1AT, United Kingdom. (1)
Professor and Director, School of Neuroscience, Virginia Tech., Blacksburg, VA, USA (1)
Fondazione Pisana per la Scienza (1)
Department of Neuroscience, Tufts University School of Medicine (1)
Department of Neurology School of Medicine Oregon Health & Science University Portland, OR, USA (1)
Mass Spectrometry Technology Access Center at the McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO, USA (1)
Inserm UNIS UMR_S 1072 51 Boulevard Pierre Dramard 13015 Marseille FRANCE (1)
Department of Biomedical Science Centre for Membrane Interactions and Dynamics (CMIAD) Firth Court, Western Bank The University of Sheffield Sheffield S10 2TN United Kingdom (1)
Bourne Laboratory, Department of Biological Science, Royal Holloway University of London, Egham, Surrey, TW20 OEX, UK (1)
Epilepsy Research Laboratory Department of Biomedical Sciences College of Veterinary Medicine Iowa State University Ames Iowa 50011-1250 USA (1)
Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, 08028 Barcelona, Spain (1)
Life Sciences (1)
UCD School of Biomolecular and Biomedical Science, University College Dublin, Belfield, Dublin 4, Ireland (1)
Department of Neurology, Xiangya Hospital, Central South University (1)
Professor at Daegu Gyeongbuk Science & Technology (DGIST), New Biology Department. (1)
Department of Pharmacology, Alberta Diabetes Institute, University of Alberta (1)
Div. Cell Biology, Biocenter, Medical University Innsbruck, Austria (1)
Goethe University Frankfurt, Institute of molecular systems medicine (1)
Department of Cellular Biology and Pathology, Instituto de Neurociencias de Castilla y León (INCyL), Laboratory Nº12 (1)
Department of Physiology and Pharmacology Oregon Health & Science University Portland, Oregon 97210, USA (1)
Department of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, China (1)

Keyword

Diabete Mellitus (1)
Sickle Cell Disease (1)
Sjogren’s Syndrome (1)
Neglected Diseases (1)
Orphan Diseases (1)
Rare Disease Research (1)
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Hemophagocytic Lymphohistiocytosis (HLH) (1)
Behcet’s Disease (1)
Jansen metaphyseal chondrodysplasia (1)
Chronic recurrent multifocal osteomyelitis (CRMO) (1)
Hereditary Sensory and Autonomic Neuropathy (1)
Nephropathic infantile cystinosis (1)
Ocular cystinosis (1)
Spinal Bulbar Muscular Atrophy (SBMA) (1)
Mucolipidosis (1)
Mitochondrial aminoacyl-tRNA synthetases (Mt-aaRS Disorders) (1)
Shine Syndrome (1)
Intestinal Bromhidrosis Syndrome (1)
Autosomal recessive extra oral halitosis (1)
CACNA1H mutation (1)
Dimethylglycine dehydrogenase deficiency (1)

IsPrivate

False (1)

Classification

bacteria (1)

Modification

15.994915 (1)
57.021464 (1)
4-tetrahydrothiazine-3-carboxylic acid (1)

Study type

Transcription profiling by array (1842)
RNA-seq of coding RNA (134)
ChIP-chip by tiling array (129)
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Location

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India (1)
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Lipid-accumulated reactive astrocytes promote disease progression in epilepsy (Human lipidomics)

Reactive astrocytes play an important role in neurological diseases, but their molecular and functional phenotypes in epilepsy are unclear. Here, we show that in patients with temporal lobe epilepsy (TLE) and mouse models of epilepsy, excessive lipid accumulation in astrocytes leads to the format...

2025-07-03 | MTBLS8856 | MetaboLights

Lipid-accumulated reactive astrocytes promote disease progression in epilepsy (Mice lipidomics)

2025-07-04 | MTBLS8865 | MetaboLights

Temporal neocortex mesial temporal lobe epilepsy

Ion channel splice array data collected from temporal neocortex brain tissue collected from patients with mesial temporal lobe epilepsy. Temporal cortex samples from control subjects were compared to temporal neocortex of patients with mesial temporal lobe epilepsy

ORGANISM(S): Homo sapiens

2010-06-11 | E-GEOD-6773 | biostudies-arrayexpress

Temporal lobe epilepsy and Alzheimer's disease

This SuperSeries is composed of the following subset Series: GSE6771: Temporal Cortex Control (mesial temporal lobe epilepsy control) GSE6773: Temporal neocortex mesial temporal lobe epilepsy GSE6774: Temporal Cortex Control (Alzheimer's disease control) GSE6775: Temporal Cortex Alzheimer's Disease ...

ORGANISM(S): Homo sapiens

2007-01-23 | E-GEOD-6834 | biostudies-arrayexpress

Localized Proteomic Differences in Choroid Plexus of Alzheimers Disease and Epilepsy Patients

Alzheimers disease and epilepsy are reciprocally related. Among sporadic AD patients, seizures occur in 10-22 percent, and subclinical epileptiform abnormalities occur in 22-5 percent. Cognitive deficits, with prominent short-term memory impairments, occur in most epilepsy patients. Common neurophys...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2023-02-27 | MSV000091370 | MassIVE

Molecular alterations in areas generating fast ripples in an animal model of temporal lobe epilepsy

The molecular basis of epileptogenesis is poorly characterized. Studies in humans and animal models have identified an electrophysiological signature that precedes the onset of epilepsy, which has been termed fast ripples (FRs) based on its frequency. Multiple lines of evidence implicate regions gen...

ORGANISM(S): Rattus norvegicus

2015-05-01 | E-GEOD-68430 | biostudies-arrayexpress

Transcription profiling of human hippocampi from epilepsy patients with and without hippocampal sclerosis and autopsy controls

Genome wide gene expression was compared between nonHS, HS temporal lobe epilepsy patients (TLE) and autopsy control hippocampi in a 3-way analysis. In many TLE patients the hippocampus is subject to massive neuronal damage, gliosis and hippocampal sclerosis (HS), while in others there is no apparen...

ORGANISM(S): Homo sapiens

2008-01-01 | E-MEXP-744 | biostudies-arrayexpress

Temporal Cortex Control (mesial temporal lobe epilepsy control)

Ion channel splice array data from temporal cortex brain tissue samples collected from control subjects (no mesial temporal lobe epilepsy). Keywords: disease associated splicing changes Temporal cortex samples from control subjects were compared to temporal neocortex of patients with mesial temporal...

ORGANISM(S): Homo sapiens

2007-01-23 | E-GEOD-6771 | biostudies-arrayexpress

Characterization of metabolomics profile changes during development of post-traumatic epilepsy in Rat Plasma (part-I)

Not available

ORGANISM(S): Rattus norvegicus

ST001020 | MetabolomicsWorkbench

Characterization of metabolomics profile changes during development of post-traumatic epilepsy in Rat Brain Tissue (part-III)

Not available

ORGANISM(S): Rattus norvegicus

ST001022 | MetabolomicsWorkbench

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