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MetabolomicsMetabolomics analysis of the effect of GnRH on the pregnancy rate of ewes with estrus synchronization scheme based on progesterone

Introduction: Gonadotropin-releasing hormone (GnRH) is widely used in the timed artificial insemination program of sheep industry, but there is still controversy about the effect of GnRH on pregnancy rate in the process of artificial insemination. Our research shows that the use of GnRH reduces t...

2024-08-12 | MTBLS10318 | MetaboLights
MetabolomicsMulti-omics analysis reveals maternal gut microbiota-derived short-chain fatty acids and progesterone are associated with offspring birth weight in sows

Piglet birth weight is a key determinant of preweaning survival and subsequent growth performance, yet the role of maternal gut microbiota in relation to offspring birth weight in sows remains incompletely characterized. This study aimed to investigate the association between maternal gut microbi...

2026-02-22 | MTBLS13791 | MetaboLights
TranscriptomicsTranscription profiling of effects of progesterone-withdrawal on uteri from decidualized mice over 4 time-points
Effect of progesterone-withdrawal in decidualized mice over 4 time-points.
ORGANISM(S): Mus musculus 
2006-12-08 | E-MEXP-932 | biostudies-arrayexpress
TranscriptomicsProgesterone-regulated genes in immune cells: Regulation of T cell genes by progesterone
We examined the global gene expression pattern of T cells regulated by progesterone to gain further insights into the regulatory mechanisms of progesterone. We found 325-347 cord blood T cell genes up or down-regulated by P4 in the presence or absence of exogenous TGFb1. Peripheral blood T cells wer...
ORGANISM(S): Homo sapiens 
2012-03-02 | E-GEOD-22025 | biostudies-arrayexpress
TranscriptomicsDifferential effects of progesterone and medroxyprogesterone acetate on normal breast cells
Comparison between the effects of progesterone (P4) and medroxyprogesterone acetate (MPA) combined to estradiol (E2) on gene expression in normal breast cells to provide insight on their possible different impact on breast cancer risk in vivo. Total RNA obtained from cultures of normal human breast ...
ORGANISM(S): Homo sapiens 
2011-05-30 | E-GEOD-23500 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat ovary in culture reveals interactions between progesterone and tumor necrosis factor-alpha in the regulation of primordial follicle assembly
Follicle assembly is the process by which groups or ‘nests’ of oocytes break down to form primordial follicles. The size of the primordial follicle pool is the major determinant of the reproductive lifespan of a female. Previously, progesterone (P4) has been shown to inhibit follicle assembly,...
ORGANISM(S): Rattus norvegicus 
2008-06-16 | E-GEOD-8238 | biostudies-arrayexpress
MetabolomicsProgesterone level effects on primary metabolites in uterus, blood, and ovaries (Part 1:Plasma)
Not available
ORGANISM(S): Bos taurus 
ST000322 | MetabolomicsWorkbench
MetabolomicsProgesterone level effects on primary metabolites in uterus, blood, and ovaries (Part 2:Uterine flush)
Not available
ORGANISM(S): Bos taurus 
ST000323 | MetabolomicsWorkbench
TranscriptomicsRNA-sequencing of human breast cancer cell lines treated and untreated with progesterone
To investigate the progesterone responsive long non-coding RNAs in human breast cancer cells. Cells were treated with 10nM of progesterone for 6 hours and cells were collected in Trizol for total RNA extraction. Total RNA sequencing was performed. Differential expression analysis was performed to id...
ORGANISM(S): Homo sapiens 
2024-07-08 | E-MTAB-11925 | biostudies-arrayexpress
MetabolomicsLuteal lipids regulate progesterone production and may modulate immune cell function during the estrous cycle and pregnancy
Not available
ORGANISM(S): Bos taurus 
ST001245 | MetabolomicsWorkbench
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