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Mapping prohormone processing by proteases in human enteroendocrine cells using genetically engineered organoid models
Enteroendocrine cells (EECs) secrete hormones in response to ingested nutrients to control physiological processes such as appetite and insulin release. EEC hormones are synthesized as large pre-proteins that undergo proteolytic processing through peptidases to generate bioactive peptides. Due to th...
ORGANISM(S): Homo sapiens (Human) 
2022-11-26 | PXD033369 | Pride
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