Protamines - OmicsDI

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Mus musculus (27)
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geo (35)
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pride (9)
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Tissue

Sperm (6)
Semen (3)
Testis (3)
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Disease

Male infertility (2)

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Mass Spectrometry (9)
Shotgun proteomics (6)
Top-down proteomics (3)
Gel-based experiment (2)
Mass spectrometry (1)
Data-dependent acquisition (1)
Affinity purification coupled with mass spectrometry proteomics (1)

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Liquid Chromatography Tandem MS (LC-MS/MS) (1)

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CHEBI ID

CHEBI:142277 (1)
CHEBI:142239 (1)
CHEBI:142276 (1)
CHEBI:142275 (1)
CHEBI:142274 (1)
CHEBI:142273 (1)
CHEBI:8286 (1)
CHEBI:142272 (1)
CHEBI:142271 (1)
CHEBI:108 (1)
CHEBI:89353 (1)
CHEBI:142270 (1)
CHEBI:142269 (1)
CHEBI:142268 (1)
CHEBI:7508 (1)
CHEBI:142267 (1)
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CHEBI:142266 (1)
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CHEBI:142263 (1)
CHEBI:80630 (1)
CHEBI:142262 (1)
CHEBI:142261 (1)
CHEBI:142258 (1)
CHEBI:75852 (1)
CHEBI:142257 (1)
CHEBI:88805 (1)
CHEBI:138790 (1)
CHEBI:142256 (1)

Metabolite Name

Yucalexin P8 (1)
Thr-Cys(Trioxidation) (1)
Rhodinyl phenylacetate (1)
Pollinastanol (1)
PIP(18:1(11Z)/20:4(5Z,8Z,11Z,14Z)) (1)
PIP(18:0/16:0) (1)
Phenylglucuronide (1)
Monolinolenin (9c,12c,15c) (1)
Isosojagol (1)
Isopeonidin 3-rutinoside (1)
Glycerol 1-stearate (1)
Ganoderol B (1)
Ganoderic acid F (1)
D-Pantothenoyl-L-cysteine (1)
Dilinolenin (9c,12c,15c) (1)
Dihydrofukinolide (1)
DG(14:0/20:3(8Z,11Z,14Z)/0:0) (1)
D-1-[(3-Carboxypropyl)amino]-1-deoxyfructose (1)
Calenduloside B (1)
Beta-D-Glucuronopyranosyl-(1->3)-alpha-D-galacturonopyranosyl-(1->2)-L-rhamnose (1)
Auxin a (1)
Arborinine (1)
Alpha-Rhamnorobin (1)
9-Oxo-15S-hydroxy-5Z,8(12),13E,17Z-prostatetraenoic acid (1)
6''-O-Malonyldaidzin (1)
6''-O-Acetylgenistin (1)
6''-Malonylastragalin (1)
2,3-Dihydro-2,3-dihydroxy-4-(4-methoxyphenyl)-1H-phenalen-1-one (1)
1-(10Z-Heptadecenoyl)-sn-glycero-3-phospho-(1'-myo-inositol) (1)
(Z)-4',6-Dihydroxyaurone 6-glucoside (1)

First Public Date

2014 (8)
2013 (6)
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2019 (3)
2018 (3)
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2020 (2)
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2017 (1)
2016 (1)
2015 (1)

Study type

ChIP-chip by tiling array (5)
Methylation profiling by high throughput sequencing (3)
ChIP-seq (2)
Transcription profiling by array (2)
RNA-seq of coding RNA (2)

Release Date

2014 (11)
2023 (11)
2015 (10)
2022 (8)
2025 (7)
2024 (7)
2021 (7)
2013 (6)
2016 (6)
2010 (5)
2018 (5)
2020 (4)
2019 (4)
2009 (3)
2011 (3)
2008 (3)
2005 (3)
2017 (2)
2012 (2)
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2006 (1)
2004 (1)
2003 (1)
2001 (1)

Lab affiliation

EDyP (2)
Mass Spectrometry and Proteomics Core Facility Institute for Research in Biomedicine (IRB Barcelona) (1)
Studying the Dynamics of Proteomes, Large-Scale Biology, CEA Grenoble (1)
Department of Human Genetics, University of Michigan, USA (1)
University of Michigan (1)
Molecular Biology of Reproduction and Development Research Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica (FCRB), Faculty of Medicine and Health Sciences, University of Barcelona Biochemistry and Molecular Genetics Service, Hospital Clínic, Barcelona (1)
Mass Spectrometry & Proteomics Core Facility (MSPCF) Institute for Research in Biomedicine (IRB Barcelona) Barcelona Institute of Science and Technology (BIST) C/ Baldiri Reixac, 10-12 08028 Barcelona - Spain (1)
Department of Developmental Pathology, Institute of Pathology, University Hospital Bonn, Germany (1)

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SPAG17 mediates nuclear translocation of protamines during spermiogenesis.

Not available

S-EPMC10520709 | biostudies-literature

Histone H1 and the origin of protamines.

Not available

S-EPMC384709 | biostudies-literature

Entropy based analysis of vertebrate sperm protamines sequences: evidence of potential dityrosine and cysteine-tyrosine cross-linking in sperm protamines.

Not available

S-EPMC7126135 | biostudies-literature

Epigenetic marking of sperm by post-translational modification of histones and protamines.

Not available

S-EPMC3904194 | biostudies-literature

Proteomic analysis of human sperm protamines from men with and without infertility

The objective of this study was to provide a comprehensive assessment of protamine isoforms and modifications in human sperm with the aim of identifying how protamine modifications/isoforms are altered in men with reduced sperm motility and low sperm count. Sperm samples from 18 men with prior repor...

ORGANISM(S): Homo sapiens (Human)

2025-05-06 | PXD046041 | Pride

Protamines from liverwort are produced by post-translational cleavage and C-terminal di-aminopropanelation of several male germ-specific H1 histones.

Not available

S-EPMC6827293 | biostudies-literature

The protamines of the spider Steatoda sp. provide an example of liquid-liquid phase separation chromatin transitions during spermiogenesis.

Not available

S-EPMC11607694 | biostudies-literature

The nuclear form of glutathione peroxidase 4 colocalizes and directly interacts with protamines in the nuclear matrix during mouse sperm chromatin assembly.

Not available

S-EPMC4160342 | biostudies-literature

Replacement by Drosophila melanogaster protamines and Mst77F of histones during chromatin condensation in late spermatids and role of sesame in the removal of these proteins from the male pronucleus.

Not available

S-EPMC1168805 | biostudies-literature

Protamine characterization by top-down proteomics: Boosting proteoform identification with DBSCAN

Protamines replace histones as the main nuclear protein in sperm cells having a crucial role in compacting the paternal genome. Human spermatozoa contain the protamine 1 (P1) and the family of protamine 2 (P2) proteins. Alterations in protamine PTMs or on the P1/P2 ratio could be associated with mal...

ORGANISM(S): Homo sapiens (Human)

2021-05-13 | PXD024405 | Pride

Male infertility sperm protamine lc-ms/ms top down proteomics proteoform post-translational modifications bioinformatics dbscan.

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