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MetabolomicsDetoxification metabolic adaptation of Bombyx mori to artificial diet and functional study of key detoxification gene BmGSTd2

The exceptional adaptability of insects to diverse food sources is central to their survival and evolutionary success. However, the molecular mechanisms underlying this rapid adaptation remain largely uncharacterized. In this study, adaptive phenotypic, transcriptomic, and metabolomic differences...

2026-01-27 | MTBLS13782 | MetaboLights
MetabolomicsGlycosylation-mediated detoxification of zearalenone by the Tibetan yeast Hannaella zeae: Multi-omics insights into its dual-function mechanism

This study investigated the detoxification of zearalenone (ZEN) by the Tibetan Plateau yeast Hannaella zeae via untargeted LC-MS/MS-based metabolomics. H. zeae was cultured in NYDB medium with ZEN supplementation, and samples were harvested after 36 h of incubation for metabolomic analysis. The c...

2026-08-20 | MTBLS15233 | MetaboLights
MetabolomicsUnveiling superior phenol detoxification and degradation ability in Candida tropicalis SHC-03: A comparative study with Saccharomyces cerevisiae BY4742

This study examined the phenol degradation capabilities and oxidative stress responses of Candida tropicalis SHC-03, demonstrating its metabolic superiority and resilience compared to Saccharomyces cerevisiae BY4742 in a culture medium with phenol as the sole carbon source. Through comparative gr...

2024-10-04 | MTBLS10757 | MetaboLights
ModelsTalemi2014 - Arsenic toxicity and detoxification mechanisms in yeast
Talemi2014 - Arsenic toxicity and detoxification mechanisms in yeast The model implements arsenite (AsIII) transport regulation, its distribution within main cellular AsIII pools and detoxification. The intracellular As pools considered are free AsIII (AsIIIin), protein-bound AsIII (AsIIIprot), glut...
2024-09-02 | BIOMD0000000547 | BioModels
TranscriptomicsTranscriptional analysis of development and detoxification in Culex pipiens quinquefasciatus
The genomes of three major mosquito vectors of human diseases, including Anopheles gambiae, Aedes aegypti, and Culex pipiens quinquefasciatus, have been previously sequenced. C. p. quinquefasciatus has the largest number of predicted protein-coding genes, which partially results from the expansion o...
ORGANISM(S): Culex quinquefasciatus 
2012-12-30 | E-GEOD-35744 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Aedes aegypti treated with permethrin to identify detoxification genes
Genomic analysis of detoxification genes in the mosquito Aedes aegypti.
ORGANISM(S): Aedes aegypti 
2008-02-09 | E-TABM-413 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of insecticide susceptible and resistant strains of Aedes aegypti to identify detoxification genes
Genomic analysis of detoxification genes in the mosquito Aedes aegypti
ORGANISM(S): Aedes aegypti 
2008-02-09 | E-TABM-414 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Anopheles gambiae midgut and fat bodies 1 and 11 days post Plasmodium berghei infection to investigate responses in detoxification genes
Detoxification genes were assayed for their response to Plasmodium berghei infection at 1 and 11 days post infection in Anopheles gambiae mosquitoes.
ORGANISM(S): Anopheles gambiae 
2010-08-11 | E-MTAB-195 | biostudies-arrayexpress
TranscriptomicsAn Ustilago maydis gene involved in H2O2 detoxification is required for virulence
The fungus Ustilago maydis is a biotrophic pathogen of corn. In its genome we have identified an ortholog of YAP1 from Saccharomyces cerevisae which regulates the oxidative stress response in this organism. yap1 mutants of U. maydis displayed higher sensitivity to H2O2 than wild type cells and their...
ORGANISM(S): Ustilago maydis 
2010-06-11 | E-GEOD-7518 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse liver and kidney from PAR bZip triple knockout mice to wild-type or heterozygous mutant mice to identify genes contributing to the morbidity of PAR bZIP triple KO mice and circadian liver detoxification
The PAR-domain basic leucine zipper (PAR bZip) transcription factors DBP, TEF, and HLF accumulate in a highly circadian manner in several peripheral tissues, including liver and kidney. Mice devoid of all three of these proteins are born at expected Mendelian ratios, but are epilepsy-prone, age at a...
ORGANISM(S): Mus musculus 
2006-12-20 | E-MEXP-565 | biostudies-arrayexpress
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