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MetabolomicsTranscriptomic and metabolomic data of goat ovarian and uterine tissues during sexual maturation (Ovarian data)

The ovaries and uterus are crucial reproductive organs in mammals, and their coordinated development ensures the normal development of sexual maturity and reproductive capacity. This study aimed to comprehensively capture the different physiological stages of the goat's sexual maturation by selec...

2024-05-30 | MTBLS9794 | MetaboLights
MetabolomicsTranscriptomic and metabolomic data of goat ovarian and uterine tissues during sexual maturation (Uterine data)

The ovaries and uterus are crucial reproductive organs in mammals, and their coordinated development ensures the normal development of sexual maturity and reproductive capacity. This study aimed to comprehensively capture the different physiological stages of the goat's sexual maturation by selec...

2024-05-30 | MTBLS9795 | MetaboLights
MetabolomicsMetabolomics reveals impaired maturation of HDL particles in adolescents with hyperinsulinaemic androgen excess
Hyperinsulinaemic androgen excess (HIAE) in prepubertal and pubertal girls usually precedes a broader pathological phenotype in adulthood that is associated with anovulatory infertility, metabolic syndrome and type 2 diabetes. The metabolic derangements that determine these long-term health risks re...
2015-04-09 | MTBLS103 | MetaboLights
MetabolomicsPKA regulates stress granule maturation to allow timely recovery after prolonged starvation
Cells have evolved multiple strategies to survive environmental stress conditions. This includes the formation of membrane-less cytoplasmic ribonucleoprotein structures called stress granules that sequester and protect mRNAs encoding many housekeeping genes. Stress granules are not static biomolecul...
2026-06-16 | MTBLS13923 | MetaboLights
MetabolomicsDelayed gut microbiota maturation in the first year of life is a hallmark of pediatric allergic disease
Allergic diseases affect millions of people worldwide. An increase in their prevalence has been associated with alterations in the gut microbiome, i.e., the microorganisms and their genes within the gastrointestinal tract. Maturation of the infant immune system and gut microbiota occur in parallel; ...
2024-10-24 | MTBLS7919 | MetaboLights
MetabolomicsComprehensive multi-omics analysis reveals the influence of epigenetic mechanisms on porcine oocyte maturation
In vitro maturation (IVM) oocyte is a key component of assisted reproduction in pigs. Asynchronous nucleoplasmic maturation and incomplete cytoplasmic maturation is one of the key factors for impaired maturation and quality of oocytes matured in vitro. Although Single-omics techniques have been appl...
2025-08-27 | MTBLS12325 | MetaboLights
MetabolomicsA multi-omic profiles of fruits regarding the maturation of Olive (Olea europaea L.) (GC-MS assay)
Olive (Olea europaea) has a long history of medicinal and nutritional values own to it rich in polyphenol and fatty acids (FAs) in fruits. In order to better understand the biosynthesis important of these metabolites, we generated comprehensive Iso-Seq full-length and illumina RNA-seq transcrip...
2019-05-07 | MTBLS855 | MetaboLights
MetabolomicsA multi-omic profiles of fruits regarding the maturation of Olive (Olea europaea L.) (Polyphenols UPLC-MS assay)
Olive (Olea europaea) has a long history of medicinal and nutritional values own to it rich in polyphenol and fatty acids (FAs) in fruits. In order to better understand the biosynthesis important of these metabolites, we generated comprehensive Iso-Seq full-length and illumina RNA-seq tr...
2019-05-07 | MTBLS814 | MetaboLights
MetabolomicsA multi-omic profiles of fruits regarding the maturation of Olive (Olea europaea L.) (Tyrosol only UPLC-MS assay)
Olive (Olea europaea) has a long history of medicinal and nutritional values own to it rich in polyphenol and fatty acids (FAs) in fruits. In order to better understand the biosynthesis important of these metabolites, we generated comprehensive Iso-Seq full-length and illumina RNA-seq transcrip...
2019-07-26 | MTBLS1127 | MetaboLights
MetabolomicsA multi-omics dataset of heat-shock response in the yeast RNA binding protein Mip6 (NMR assay)

Gene expression is a biological process regulated at different molecular levels, including chromatin accessibility, transcription, and RNA maturation and transport. In addition, these regulatory mechanisms have strong links with cellular metabolism. Here we present a multi-omics dataset that capt...

2020-02-14 | MTBLS1320 | MetaboLights
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