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MetabolomicsMapping of the viral shunt across widespread coccolithophore blooms using metabolic biomarkers

The viral shunt is a fundamental ecosystem process which diverts the flux of organic carbon fixed through photosynthesis during algal bloom events from heterotrophic grazers to bacteria. Through the extracellular release of metabolites, lytic viral infections supply 2-10% of photosynthetically fi...

2025-10-08 | MTBLS11597 | MetaboLights
TranscriptomicsSurface sensing in Vibrio parahaemolyticus triggers a programme of gene expression that promotes colonization and virulence
Vibrio parahaemolyticus senses surfaces via impeded rotation of its polar flagellum. We have exploited this surface-sensing mechanism to trick the organism into thinking it is on a surface when it is growing in liquid. This facilitated studies of global gene expression in a way that avoided many of ...
ORGANISM(S): Vibrio parahaemolyticus 
2010-12-15 | E-GEOD-18763 | biostudies-arrayexpress
ProteomicsA Chemical Proteomics Approach for Global Mapping of Functional Lysines on Cell Surface of Living Cell
Cell surface proteins are responsible for many crucial physiological roles, and they are also the major category of drug targets as the majority of therapeutics target membrane proteins on the surface of cells to alter cellular signaling. How-ever, despite its great significance, ligand discovery ag...
ORGANISM(S): Homo Sapiens 
2024-03-01 | PXD042888 |
TranscriptomicseQTL mapping in Lake Whitefish Species Pairs.
Mapping of expression quantitative trait loci (eQTL) is a powerful means for elucidating the genetic architecture of gene regulation. Yet, eQTL mapping has not been applied towards investigating the regulation architecture of genes involved in the process of population divergence, ultimately leading...
ORGANISM(S): Coregonus clupeaformis 
2008-09-01 | E-GEOD-11378 | biostudies-arrayexpress
GenomicsGenomic mapping of cAMP receptor protein binding in relation to transcriptional start sites in Mycobacterium tuberculosis
In this study we have used ChIPseq analysis to perform comprehensive mapping of the binding profile of the cAMP receptor protein (CRPMt) of M. tuberculosis combined with RNAseq studies to further investigate the transcriptional response following crp gene deletion and under alternative growth condi...
ORGANISM(S): Mycobacterium tuberculosis 
2014-06-24 | E-MTAB-2390 | biostudies-arrayexpress
TranscriptomicsENCODE Transcript Mapping for Total RNA from Human NB4 Cells untreated, treated with RA, and treated with TPA
Transcript Mapping on Affymetrix ENCODE arrays for Total RNA from 4 different samples (2 or 3 technical replicates of each). All of the four same NB4 samples have also been treated with Retanoic Acid (RA) (2 or 3 technical replicates of each). Three of the four same NB4 samples have also been treate...
ORGANISM(S): Homo sapiens 
2010-06-10 | E-GEOD-2679 | biostudies-arrayexpress
GenomicsGenome-wide mapping of HATs and HDACs in human CD4+ T cells
Histone acetyltransferases (HATs) and deacetylases (HDACs) function antagonistically to control histone acetylation. As acetylation is a histone mark for active transcription, HATs have been associated with active and HDACs with inactive genes. We describe here genome-wide mapping of HATs and HDACs ...
ORGANISM(S): Homo sapiens 
2009-08-20 | E-GEOD-15735 | biostudies-arrayexpress
ProteomicsData in support of the equine mesenchymal stem cell surface proteome for mining for new surface markers
Regenerative medicine in aims to restore structure and function to tissues or organs damaged by time, disease or injury. Stem cells have great potential for tissue repair and regeneration, why they are intensely investigated in equine clinical research. However, before any type of stem cell can be a...
ORGANISM(S): Equus caballus (Horse) 
2018-11-04 | PXD008884 | Pride
Horse stem cells membrane 
ProteomicsGrowth condition-dependent cell surface proteome analysis of Enterococcus faecium
Using a proteolytic shaving approach we identified differentially expressed surface exposed proteins of E. faecium cells after growth in different conditions.
ORGANISM(S): Enterococcus Faecium E1162 (ncbitaxon:535206) 
2015-07-07 | MSV000079184 | MassIVE
ProteomicsInferring Epitopes of a Polymorphic Antigen Amidst Broadly Cross-Reactive Antibodies Using Protein Microarrays: a Study of OspC Proteins of Borrelia burgdorferi
Epitope mapping studies aim to identify the binding sites of antibody-antigen interactions to enhance the development of vaccines, diagnostics and immunotherapeutic compounds. However, mapping is a laborious process employing time- and resource-consuming M-bM-^@M-^Xwet benchM-bM-^@M-^Y techniques o...
ORGANISM(S): Peromyscus leucopus 
2013-04-12 | E-GEOD-45996 | biostudies-arrayexpress
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