Protein unfolding

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Visualization of the Cdc48 AAA+ ATPase protein unfolding pathway: Substrate Identification

The Cdc48 AAA+ ATPase is an abundant and essential enzyme that unfolds substrates in multiple protein quality control pathways. The enzyme includes two conserved AAA+ ATPase cassettes, D1 and D2, that assemble as hexameric rings with D1 stacked above D2. Here, we report an ensemble of structures of ...

ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast)

2024-10-17 | PXD048280 | Pride

Human Shp1 pulldown

Snapshots of urea-induced early structural changes and unfolding of an ankyrin repeat protein at atomic resolution.

Not available

S-EPMC9703593 | biostudies-literature

Unfolding study of a trimeric membrane protein AcrB.

Not available

S-EPMC4088973 | biostudies-literature

Characterization of protein unfolding with solid-state nanopores.

Not available

S-EPMC4188535 | biostudies-literature

Mitochondrial unfolding protein CLPX is required for oocyte competence during ovarian aging

PRJNA1202134 | ENA

Modular DNA origami compartments for the engineering of a protein unfolding and degradation pathway

Within the cell, chemical reactions are often confined and organized through a modular architecture. In this project, a cell-free nanoscale model of the proteasome was analyzed that exploits this compartmentalization principle to perform regulated protein unfolding and degradation. To this end, the ...

ORGANISM(S): Homo sapiens (Human)

2024-07-25 | PXD050816 | Pride

Directional degradation Dna origami compartments Nanofactories

Genome-wide probing of RNA structure reveals active unfolding of mRNA structures in vivo

We present an approach for globally monitoring RNA structure in native conditions in vivo with single nucleotide precision. This method is based on in vivo modification with dimethyl sulfate (DMS), which reacts with unpaired adenine and cytosine residues9, followed by deep sequencing to monitor modi...

ORGANISM(S): Homo sapiens

2013-12-15 | E-GEOD-45803 | biostudies-arrayexpress

Mechanical unfolding of an ankyrin repeat protein.

Not available

S-EPMC2849098 | biostudies-literature

A theoretical search for folding/unfolding nuclei in three-dimensional protein structures.

Not available

S-EPMC18028 | biostudies-literature

Structural basis for unfolding pathway-dependent stability of proteins: vectorial unfolding versus global unfolding.

Not available

S-EPMC2867010 | biostudies-literature

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