Proteolytic enzymes

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Unknown (1196)
Proteomics (375)
Transcriptomics (158)
Genomics (123)
Metabolomics (29)
Models (4)
Other (2)
Multiomics (1)

Organisms

Homo sapiens (116)
Mus musculus (46)
Rattus norvegicus (8)
Drosophila melanogaster (8)
Arabidopsis thaliana (7)
Paxillus involutus (4)
Chlamydomonas reinhardtii (3)
Trichophyton rubrum (3)
Xenopus laevis (2)
Caenorhabditis elegans (2)
Salmo salar (2)
Macaca mulatta (1)
Eukaryota (1)
Meloidogyne hapla (1)
Lathyrus sativus (1)
Cereibacter sphaeroides (1)
Colletotrichum higginsianum (1)
Aureococcus anophagefferens (1)
Proteus mirabilis (1)
Psychrobacter arcticus 273-4 (1)
Streptococcus mutans (1)
Clostridium botulinum (1)
Papio anubis (1)
Pseudomonas syringae pv. tomato str. DC3000 (1)
Bacillus thuringiensis Bt407 (1)
Streptococcus pyogenes (1)
Mus musculus domesticus (1)
Entamoeba histolytica (1)
Oryza sativa (1)
Bos taurus (1)

Organisms

Mus musculus (9)
Homo sapiens (9)
Saccharomyces cerevisiae (7)
Drosophila melanogaster (3)
Paxillus involutus (2)
Rattus norvegicus (2)
Arabidopsis thaliana (2)
Meiothermus ruber H328 (1)
Fascioloides magna (1)
Rhizopus sp. FBL578 (1)
Exiguobacterium abrahamii (1)
Trichophyton benhamiae (1)
Adenoviridae (1)
Shewanella polaris (1)
Bacillus subtilis Miyagi-4100 (1)
Mucor flavus (1)
Streptomyces sp. SS713 (1)
Trichophyton rubrum (1)
Tenacibaculum mesophilum (1)
Lysobacter enzymogenes (1)
Fasciola hepatica (1)
Oncorhynchus mykiss (1)
Priestia megaterium (1)
Prunus persica (1)
Bombyx mori (1)
Danio rerio (1)

Repository

pride (239)
biostudies-arrayexpress (128)
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ENA (66)
EGA (46)
geo (42)
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jPOST (11)
PanoramaPublic (7)
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GPMDB (2)
PAXDB (1)
PeptideAtlas (1)

Tissue

Cell culture (38)
Epithelial cell (17)
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Lung (7)
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T cell (3)
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Hepatocyte (2)
Ileum (2)
Mandibular organ (2)
Muscle (2)

Disease

Disease free (7)
Cervix carcinoma (6)
Acute leukemia (3)
COVID-19 (3)
Not Available (2)
Breast cancer (2)
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Influenza (2)
Malignant neoplasm of ovary (2)
Wounds and Injuries (2)
Neurodegenerative disease (1)
Alzheimer's disease (1)
Alpha-1 antitrypsin deficiency-related emphysema (1)
Psoriasis vulgaris (1)
Healthy (1)
Amyloidosis (1)
Brain cancer (1)
Cystic echinococcosis (1)
Cystic fibrosis (1)
Facioscapulohumeral muscular dystrophy (1)
Fragile X syndrome (1)
Hepatoblastoma (1)
Intestinal schistosomiasis (1)
Lymphoma (1)
Male infertility (1)
Mixed disorder as reaction to stress (1)
Osteoarthritis (1)
Parkinson's disease (1)
Pre-eclampsia (1)

Technology Type

Mass Spectrometry (239)
Shotgun proteomics (131)
Bottom-up proteomics (56)
Data-dependent acquisition (26)
Mass spectrometry (23)
Gel-based experiment (19)
Data-independent acquisition (18)
Affinity purification coupled with mass spectrometry proteomics (17)
SWATH MS (13)
Top-down proteomics (8)
Chemical cross-linking coupled with mass spectrometry proteomics (6)
Mass spectrometry assay (5)
MSE (2)
ILLUMINA, Illumina HiSeq 2000 (1)
NMR spectroscopy (1)
All-ion fragmentation (1)
DiaPASEF (1)
HDMSE (1)
Metaproteomics (1)
SRM/MRM (1)

Instrument Platform

Q Exactive (20)
Orbitrap Fusion Lumos (15)
Illumina NovaSeq 6000 (14)
LTQ (14)
LTQ Orbitrap Velos (12)
LTQ Orbitrap Elite (10)
LTQ Orbitrap (9)
NextSeq 500 (8)
Q Exactive Plus (7)
NextSeq 550 (4)
LTQ Orbitrap XL (4)
LTQ XL (4)
Orbitrap Exploris 480 (4)
DELL PRECISION 7500 (2)
Manual (2)
10x Genomics Chromium (2)
Illumina NovaSeq X (2)
None (2)
Illumina MiniSeq (2)
Illumina HiSeq 2500 (2)
Illumina HiSeq 2000 (2)
Instrument (2)
KAPA RNA HyperPrep Kit (1)
Nanodrop 2000c spectrophotometer (1)
10X Chromium Controller (1)
Scanning hardware (1)
RNeasy Mini Kit (1)
N/a (1)
N/A (1)
DNBSEQ-G400 (1)

Publication Date

2024 (63)
2025 (58)
2026 (54)
2023 (49)
2022 (47)
2020 (42)
2021 (38)
2019 (30)
2016 (22)
2015 (22)
2018 (21)
2010 (19)
2013 (15)
2007 (15)
2017 (14)
2011 (11)
2012 (10)
2009 (10)
2008 (9)
2006 (8)
2014 (7)
2005 (6)
2002 (1)

UNIPROT ID/AC

P05067 (1)
6PGL_HELPY (1)
85962.C694_00040 (1)
85962.C694_00275 (1)
85962.C694_00510 (1)
85962.C694_00935 (1)
85962.C694_01080 (1)
85962.C694_01205 (1)
85962.C694_02750 (1)
85962.C694_03200 (1)
85962.C694_03205 (1)
85962.C694_03530 (1)
85962.C694_03705 (1)
85962.C694_03715 (1)
85962.C694_03730 (1)
85962.C694_04635 (1)
85962.C694_04640 (1)
85962.C694_05100 (1)
85962.C694_05145 (1)
85962.C694_05150 (1)
85962.C694_05210 (1)
85962.C694_05650 (1)
85962.C694_05655 (1)
85962.C694_05750 (1)
85962.C694_05755 (1)
85962.C694_06925 (1)
85962.C694_06985 (1)
85962.C694_07065 (1)
85962.C694_07285 (1)
85962.C694_07295 (1)

CHEBI ID

CHEBI:16610 (7)
CHEBI:7916 (7)
CHEBI:16750 (7)
CHEBI:17154 (7)
CHEBI:27897 (7)
CHEBI:25017 (6)
CHEBI:28044 (6)
CHEBI:16393 (6)
CHEBI:16704 (6)
CHEBI:15891 (6)
CHEBI:18257 (6)
CHEBI:17964 (6)
CHEBI:16235 (6)
CHEBI:15428 (6)
CHEBI:17562 (6)
CHEBI:16335 (6)
CHEBI:16919 (6)
CHEBI:15354 (6)
CHEBI:17596 (6)
CHEBI:17368 (6)
CHEBI:16027 (5)
CHEBI:17822 (5)
CHEBI:26271 (5)
CHEBI:22660 (5)
CHEBI:27570 (5)
CHEBI:18186 (5)
CHEBI:16811 (5)
CHEBI:16761 (4)
CHEBI:15422 (1)
CHEBI:26523 (1)

Metabolite Name

Pyroglutamic acid (6)
Proline (5)
Methionine (5)
Creatine (5)
Valine (5)
Leucine (5)
Putrescine (5)
Spermidine (5)
Propionic acid (5)
L-Tyrosine (5)
L-Phenylalanine (5)
Phosphate (4)
Uridine (4)
Tryptophan (4)
Taurine (4)
Serine (4)
Nicotinamide (4)
Lysine (4)
Inosine (4)
Hypoxanthine (4)
Guanosine (4)
Guanine (4)
Citrulline (4)
Asparagine (4)
Adenine (4)
Histidine (4)
Xanthine (4)
Phenylalanine (4)
Tyrosine (4)
Threonine (4)

First Public Date

2014 (21)
2024 (10)
2026 (6)
2022 (6)
2019 (5)
2023 (4)
2020 (4)
2017 (4)
2013 (2)
2025 (1)
2018 (1)
2016 (1)
2015 (1)

Modelling Approach

Ordinary differential equation model (4)

Lab affiliation

Professor, Deputy Head of Centre Novo Nordisk Foundation Center for Protein Research University of Copenhagen Copenhagen, DENMARK (7)
Chair of Biochemistry II, Theodor Boveri-Institute, Biocenter, University of Würzburg, Würzburg, Germany (4)
Stowers Institute for Medical Research (4)
Novo Nordisk Foundation, Center for Protein Research Faculty of Health and Medical Sciences University of Copenhagen Blegdamsvej 3B, DK-2200 Copenhagen N Denmark (3)
University Clinic for Poultry and Fish Medicine, University of Veterinary Medicine, Vienna, Austria (3)
Biochemistry and Functional Proteomics, Institute of Biology II, Faculty of Biology, University of Freiburg, 79104 Freiburg, Germany (2)
Boston University Medical Campus 670 Albany St., Rm. 509 Boston, MA 02118 USA (2)
Department of Chemistry and Biomolecular Sciences, University of Ottawa, Canada (2)
Department of Pharmaceutical Chemistry and Bioanalytics Institute of Pharmacy Martin Luther University Halle-Wittenberg Halle (Saale), Germany (2)
Faculty of Chemistry, Biotechnology and Food Science. Norwegian University of Life Sciences. (2)
Institute of Biochemistry II, University Hospital, Goethe University, Frankfurt, Germany (2)
LEO Foundation Center for Cutaneous Drug Delivery Department of Pharmacy University of Copenhagen Denmark (2)
Max Planck Institute of Biophysics Max Planck Institute for Brain Research (2)
School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales 2052, Australia (2)
School of Life Sciences, University of Dundee, Dundee, UK (2)
Systems Biology Initiative, School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales 2052, Australia (2)
1. Centre for Immune Regulation and Department of Immunology, University of Oslo and Oslo University Hospital - Rikshospitalet, 0424 Oslo, Norway 2. Proteomics Core Facility, Oslo University Hospital-Rikshospitalet, 0424 Oslo, Norway (1)
1. Division of Bioanalytical Chemistry, Department of Chemistry and Pharmaceutical Sciences, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands; 2. Centre for Analytical Sciences Amsterdam (CASA), The Netherlands (1)
1Neonatal Research, Murdoch Children’s Research Institute, Parkville, Australia 2Department of Paediatrics, University of Melbourne, Melbourne, Australia (1)
Adele Niessen Professor of Ophthalmology Vice Chair for Research FM Kirby Center for Molecular Ophthalmology Scheie Eye Institute University of Pennsylvania (1)
Amyloidosis Treatment and Research Center, Fondazione IRCCS Policlinico San Matteo and University of Pavia, Italy (1)
B CUBE Technische Universität Dresden Tatzberg 41 03107 Dresden (1)
BOKU University, Department of Agricultural Sciences, Institute of Environmental Biotechnology (1)
Baker Heart & Diabetes Inst. (1)
Baker Heart & Diabetes Institute and Murdoch Childrens Research Institute (pmpf@unimelb.edu.au) (1)
Bavarian Center for Biomolecular Mass Spectrometry (BayBioMS) Technical University Munich (TUM) Gregor-Mendel-Strasse 4 85354 Freising Germany (1)
Bavarian Center for Biomolecular Mass Spectrometry (BayBioMS) Technical University Munich (TUM) Gregor-Mendel-Straße 4 85354 Freising (1)
Bavarian Center for Biomolecular Mass Spectrometry (BayBioMS) Technische Universität München (TUM) Gregor-Mendel-Straße 4 85354 Freising GERMANY (1)
Bavarian Center for Biomolecular Mass Spectrometry (BayBioMS) Technische Universität München Gregor-Mendel-Straße 4 85354 Freising GERMANY (1)
Bavarian Center for Biomolecular Mass Spectrometry (BayBioMS), Freising, TU Munich (1)

IsPrivate

False (4)

Classification

fungi (4)
helminths (1)
viruses (1)

Modification

N6 (2)
N6-dimethyl-L-lysine (2)
4x(2)H labeled dimethylated residue (1)
Not available (1)

Study type

Transcription profiling by array (77)
RNA-seq of coding RNA (12)
ChIP-seq (7)
RNA-seq of coding RNA from single cells (6)
Transcription profiling by SAGE (3)
Unknown experiment type (3)
RIP-seq (3)
ATAC-seq (2)
Methylation profiling by high throughput sequencing (2)
RNA-seq of total RNA (2)
Animal - One-color microarray (1)
ChIP-chip by tiling array (1)
MicroRNA profiling by high throughput sequencing (1)
Comparative genomic hybridization by array (1)
Hi-C (1)
Ribo-seq (1)
ScATAC-seq (1)
Single nucleus RNA sequencing (1)
DNA-seq (1)
Methylation profiling by array (1)
Proteomic profiling by array (1)

Release Date

2022 (124)
2021 (93)
2025 (90)
2020 (85)
2018 (82)
2023 (80)
2024 (72)
2019 (72)
2016 (71)
2017 (60)
2015 (59)
2012 (58)
2011 (56)
2014 (49)
2010 (49)
2013 (44)
2009 (42)
2008 (25)
2026 (24)
2007 (24)
2006 (20)
2005 (15)
2003 (5)
2001 (5)
2000 (5)
2004 (4)
2002 (3)
1999 (3)
1998 (2)
1997 (1)

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Proteolytic-Resistant Self-Assembling Peptide Nanofibers Combat Specific Bacterial Infections via Trap-and-Kill

The rise in global antibiotic resistance highlights the urgent need for effective antimicrobial agents. Antimicrobial peptides (AMPs) offer a potential solution to combat bacterial resistance. However, key challenges remain in addressing the limitations of current peptide drugs and biomaterials, ...

2025-06-13 | MTBLS12424 | MetaboLights

Comparative genomic hybridization of Clostridium sporogenes and Clostridium botulinum strains

Clostridium botulinum is a heterogeneous Gram-positive species that comprises four genetically and physiologically distinct groups of bacteria that share the ability to produce botulinum neurotoxin, the most poisonous toxin known to man, and the causative agent of botulism, a severe disease of human...

ORGANISM(S): Clostridium botulinum

2007-05-23 | E-TABM-264 | biostudies-arrayexpress

Gene expression profiling in the human pathogenic dermatophyte Trichophyton rubrum during growth on proteins

Dermatophytes are highly specialized filamentous fungi which cause the majority of superficial mycoses in humans and animals. The high secreted proteolytic activity of these microorganisms during growth on proteins is assumed to be linked with their particular ability to exclusively infect keratiniz...

ORGANISM(S): Trichophyton rubrum

2008-12-30 | E-GEOD-11711 | biostudies-arrayexpress

Asparagine peptide lyases: a seventh catalytic type of proteolytic enzymes.

Not available

S-EPMC3207474 | biostudies-literature

Aminopeptidase N

Not available

S-EPMC7150183 | biostudies-literature

Angiotensin-Converting Enzyme-2

Not available

S-EPMC7150073 | biostudies-literature

The Entamoeba histolytica genome: primary structure and expression of proteolytic enzymes.