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Genome-Wide CRISPRi Screen and Proteomic Profiling Identify Key Genes Related to Ferulic Acid's Antifungal Activity
Genome-Wide CRISPRi Screen and Proteomic Profiling Identify Key Genes Related to Ferulic Acid's Antifungal Activity
Genome-Wide CRISPRi Screen and Proteomic Profiling Identify Key Genes Related to Ferulic Acid's Antifungal Activity
We performed a genome-wide screen for genetic MDM33 interaction partners. Using the opposite approach of the well known synthetic dosage lethality (screening for deletion strains in which a non-toxic overexpression is associated with a synthetic growth arrest) we screened the whole genome for genes ...
ORGANISM(S): Saccharomyces cerevisiae 
Cell division is a fundamental process for multicellula organisation. Here we report a genome-scale RNAi screen in HeLa cells designed to identify human genes important for cell division. We utilized a library of endoribonuclease-prepared siRNAs (esiRNAs) for gene-silencing and used DNA content an...
ORGANISM(S): Homo sapiens 
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