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ProteomicsProteomic analysis of NK cell-derived extracellular vesicles.
Natural killer (NK) cells contribute to immunosurveillance and first-line defense in the control of tumor growth and metastasis diffusion. NKEVs are constitutively secreted, are biologically active, reflect the protein and genetic repertoire of their originating cells and exert anti-tumor activity i...
ORGANISM(S): Homo sapiens (Human) 
2020-04-03 | PXD014894 | Pride
Proteomics natural killer cells exosomes microvesicles 
ProteomicsProteomic analysis of NK3.3-derived extracellular vesicles
Our study investigates the features and anti-tumor function of extracellular vesicles (EVs) isolated from our well described NK cell line - NK3.3 - the only published clonal, normal human cell line to date. Natural killer (NK) cells, critical for proper immune function, destroy tumor cells primaril...
ORGANISM(S): Homo sapiens (Human) 
2021-09-07 | PXD027051 | Pride
Rnf19b Extracellular vesicle Nklam Nk3.3 Exosome Leukemia Natural killer cell Ubiquitin ligase 
ProteomicsTreatment of human K562 chronic myelogenous leukemia cells with NK3.3-derived extracellular vesicles
Our study investigates the features and anti-tumor function of extracellular vesicles (EVs) isolated from our well described NK cell line - NK3.3 - the only published clonal, normal human cell line to date. Natural killer (NK) cells, critical for proper immune function, destroy tumor cells primaril...
ORGANISM(S): Homo sapiens (Human) 
2021-09-07 | PXD027221 | Pride
Rnf19b Microvesicle Extracellular vesicle Nklam Nk3.3 Exosome Leukemia Extracellular vesicles Natural killer cell Ubiquitin ligase 
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