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The colonic epithelium is a highly dynamic system important for regulation of ion and water homeostasis via absorption and secretion, and in maintaining a protective barrier between the outer milieu and the inside of our body. These processes are known to gradually change along the length of the col...
ORGANISM(S): Homo sapiens (Human) 
2014-07-31 | PXD000987 | Pride
Mammalian fertilization requires a complex interplay between a sperm cell and an oocyte. A significant proportion of these functions are mediated through the proteomic composition of the sperm surface. These proteomic constituents can present as biomarkers to control and regulate breeding of agricul...
ORGANISM(S): Bos taurus (Bovine) 
2015-03-19 | PXD001096 | Pride
The colonic epithelium is a highly dynamic system important for regulation of ion and water homeostasis via absorption and secretion, and in maintaining a protective barrier between the outer milieu and the inside of our body. These processes are known to gradually change along the length of the col...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-03-07 | MSV000079561 | MassIVE
The protein IWS1 (Interacts with SPT6 1) has been implicated in various transcription-associated processes, but whether it has a direct role in RNA polymerase (Pol) II transcription remains unclear. Here, we establish a rapid depletion system for IWS1 in human cells, and use it to elucidate its func...
ORGANISM(S): Homo sapiens (Human) 
2025-07-30 | PXD066658 | Pride
The brain extracellular matrix (ECM) regulates myelin repair and regeneration after demyelination by interacting with neuronal progenitors and immune cells. Therefore, generating and characterizing ECM scaffolds in regions with distinct neuroregenerative capacities is crucial to identify factors tha...
ORGANISM(S): Homo sapiens (Human) 
2025-05-27 | PXD062743 | Pride
Severe eosinophilic asthma is characterized by chronic airway inflammation, oxidative stress and elevated proinflammatory cytokines, especially IL-5. Mepolizumab and benralizumab are both humanized IgG antibodies directed against IL-5 signaling, directly acting on eosinophils count. Together with th...
ORGANISM(S): Homo sapiens (Human) 
2022-04-01 | PXD029793 | Pride
Summary In this project, 2717 proteins were identified. The fold-change cutoff was set when proteins with quantitative ratios above 1.5 or below 1/1.5 are deemed significant.
ORGANISM(S): Mus musculus (Mouse) 
2025-02-27 | PXD060392 | Pride
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