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TranscriptomicsTranscript profiling of Arabidopsis plasma membrane proton pump mutants
Plasma membrane proton pump maintains proton electrochemical gradient and provides energy to secondary transporters. Arabidopsis mutant plants with reduced proton pump activity grow normal under ideal growth conditions; however their growth are reduced compared with wildtype plants when placed under...
ORGANISM(S): Arabidopsis thaliana 
2015-04-01 | E-GEOD-34202 | biostudies-arrayexpress
TranscriptomicsExpression data from young and senescent HCAECs treated with proton pump inhibitors (omeprazole and lansoprazole)
Proton pump inhibitors (PPIs) are among the most frequently prescribed drugs, especially in older people. Although these drugs are usually considered safe, recent evidence suggests that high dose and/or long term use of PPIs may have several detrimental effects, including increased risk of adverse c...
ORGANISM(S): Homo sapiens 
2017-04-18 | E-GEOD-77239 | biostudies-arrayexpress
TranscriptomicsTranscript profiling of Arabidopsis plasma membrane proton pump mutants
Plasma membrane proton pump maintains proton electrochemical gradient and provides energy to secondary transporters. Arabidopsis mutant plants with reduced proton pump activity grow normal under ideal growth conditions; however their growth are reduced compared with wildtype plants when placed under...
ORGANISM(S): Arabidopsis thaliana 
2015-04-01 | GSE34202 | GEO
ProteomicsInter- and Intra-Molecular Interactions of The Arabidopsis Plasma Membrane Proton Pump Revealed Using a Mass Spectrometric-Cleavable Crosslinker
In plants and fungi, the plasma membrane proton pump (H+-ATPase) establishes an electrochemical gradient across the plasma membrane which serves as the driving force for the secondary transport of ions and nutrients across the cell membrane. This is an essential enzyme that functions in many importa...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) Saccharomyces cerevisiae (Baker's yeast) 
2023-06-01 | PXD018219 | Pride
Arabidopsis Plasma membrane protein pump Metabolic labeling Dsso Crosslinking 
GenomicsLong-term Proton Pump Inhibitor Administration Caused Physiological and Microbiota Changes in Rats
Long-term Proton Pump Inhibitor Administration Caused Physiological and Microbiota Changes in Rats
PRJEB28574 | ENA
GenomicsProton pump inhibitor treatment aggravates bacterial translocation in patients with advanced liver cirrhosis and portal hypertension
Blood microbiome and proton pump inhibitor treatment
PRJEB53045 | ENA
Genomicsgut metagenome
proton pump inhibitor in cats
PRJNA319383 | ENA
ProteomicsTransmembrane protein 184B (TMEM184B) promotes endolysosomal acidification through vesicular proton pump regulation
Disruption of endolysosomal acidification is a hallmark of several neurodevelopmental and neurodegenerative disorders. Impaired acidification causes accumulation of toxic protein aggregates and disrupts neuronal homeostasis, yet the molecular mechanisms regulating endolysosomal pH in neurons remain ...
ORGANISM(S): Homo sapiens (Human) 
2025-06-16 | PXD064977 | Pride
Vatpase Endolysosomal acidification Tmem184b 
Genomics
Murine stress, proton pump inhibitors, and the microbiome
PRJNA433163 | ENA
GenomicsTargeting ATP12A, a non-gastric proton pump alpha subunit, for idiopathic pulmonary fibrosis treatment
Targeting ATP12A, a non-gastric proton pump alpha subunit, for idiopathic pulmonary fibrosis treatment
PRJNA847950 | ENA
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