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We identified PRP4 kinase-A (PRP4ka) in a forward genetic screen based on an alternatively-spliced GFP reporter gene in Arabidopsis thaliana (Arabidopsis). Prp4 kinase, which was the first spliceosome-associated kinase shown to regulate splicing in fungi and mammals, has not yet been studied in plan...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2018-10-25 | PXD008580 | Pride
PRP4KA phosphorylates Serrate/Ars2 for degradation vs 20S proteasome to fine-tune RNA processing
We examined global expression profiles of 3-week-old prp4k3(amiR-PRP4K3) leaves compared to Col-0 using illumina sequencing. PRP4KA and its paralogs interact with Serrate (SE), a key factor in miRNA metabolism.phosphorylation of SE via PRP4KA can quickly clear accumulated SE to secure its proper amo...
ORGANISM(S): Arabidopsis thaliana 
2021-12-20 | GSE190831 | GEO
Genomics
Identification of prp4 kinase and sac3a mutations in a genetic screen for mutants altered in pre-mRNA splicing of a GFP reporter gene
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