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TranscriptomicsPulmonary alveolar macrophages (PAMs) of Tongcheng piglets response to HP-PRRSV infection in vivo
Porcine reproductive and respiratory syndrome (PRRS), caused by PRRS virus (PRRSV), is the most economically important disease in pig populations. Lung damage is one major pathological condition following PRRSV infection, often leading to animal death. In vivo, PRRSV productive infection occurs pred...
ORGANISM(S): Sus scrofa 
2012-06-30 | E-GEOD-22782 | biostudies-arrayexpress
ProteomicsThe analysis of PRRSV nucleocapsid interactome
The porcine reproductive and respiratory virus (PRRSV) is a significant swine disease, causing reproductive failure in sows and complex respiratory failure in sows and complex repiratory syndrome in pigs of all ages. PRRSV is an enveloped +ssRNA virus classified within the family Arteriviridae, whic...
ORGANISM(S): Homo sapiens (Human) 
2026-05-01 | PXD044394 | Pride
Prrsv nidovirus arterivirus nucleocapsid interactome 
ProteomicsQuantitative proteomic analysis of global protein acetylation in PRRSV infected pulmonary alveolar macrophages
Porcine reproductive and respiratory syndrome (PRRS), which caused by the porcine reproductive and respiratory syndrome virus (PRRSV), is a serious viral disease affecting global swine industry. At present, PRRSV vaccines fail to prevent this disease. Consequently, new antiviral strategies to compen...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2020-12-11 | PXD016927 | Pride
Porcine reproductive and respiratory syndrome  tandem mass tag label lc-ms  post-translational modification  acetylation. 
GenomicsSus scrofa strain:PRRSV | breed:Large Yorkashire
PRRSV-infected pocine endometrial epithelial cell Transcriptome
PRJNA486065 | ENA
TranscriptomicsRNASeq of MARC-145 or MA-104 cells infected with porcine reproductive and respiratory syndrome virus (PRRSV)-1 or PRRSV-2, harvested at 3-12 hpi
Cell lines derived from Chlorocebus sabaeus kidney were infected with an isolate of PRRSV-1 or PRRSV-2 and RNASeq was performed (this entry) in parallel with ribosome profiling (see related accession numbers). These RNASeq datasets provide information on the transcriptome of PRRSV-infected cells and...
ORGANISM(S): Chlorocebus sabaeus 
2022-03-09 | E-MTAB-10623 | biostudies-arrayexpress
GenomicsPRRSv
PRRSv resequencing project
PRJEB46770 | ENA
TranscriptomicsRibosome profiling of MARC-145 or MA-104 cells infected with porcine reproductive and respiratory syndrome virus (PRRSV)-1 or PRRSV-2, harvested at 3-12 hpi
Cell lines derived from Chlorocebus sabaeus kidney were infected with an isolate of PRRSV-1 or PRRSV-2 and ribosome profiling was performed (this entry) in parallel with RNASeq (see related accession number). These datasets were used to analyse the viral and host translatome, frameshifting on the vi...
ORGANISM(S): Chlorocebus sabaeus 
2022-03-09 | E-MTAB-10621 | biostudies-arrayexpress
TranscriptomicsWhole blood response of Pigs to infection with Porcine Reproductive and Respiratory Syndrome Virus (PRRSV)
Porcine reproductive and respiratory disease (PRRS) is the most important disease in swine industry worldwide. However, strategies such as vaccination and good biosecurity are not consistently successful to eliminate PRRSV. Although some gene expression pathways have been explored recently, host mol...
ORGANISM(S): Sus scrofa 
2012-09-26 | E-GEOD-41144 | biostudies-arrayexpress
TranscriptomicsPRRSV-infection of porcine alveolar macrophages
The goal of this study was to produce a deep, global analysis of gene expression changes that occured following infection of normal porcine alveolar macrophages (PAMs) with PRRSV. The goal was to examine the gene expression changes to help determine the mechanisms that result in reduced function an...
ORGANISM(S): Sus scrofa 
2008-09-01 | E-GEOD-10346 | biostudies-arrayexpress
ProteomicsIdentification of MHC-I presented porcine respiratory and re-productive syndrome virus (PRRSV) peptides reveals immu-nogenic epitopes within several non-structural proteins recog-nized by CD8+ T cells
Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most relevant por-cine pathogens worldwide. Active control of the disease relies on modified live virus vaccines (MLVs), as most inactivated vaccines provide very limited protection. Neutralizing antibodies occur late in infec...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2022-10-14 | PXD035499 | Pride
Porcine reproductive and respiratory syndrome virus  prrsv  arteriviridae  cd8+ t cells  im-munopeptidome  epitopes  swine leukocyte antigen class i  major histocompatibility complex class i  mass spectrometry  restimulation  intracellular cytokine staining 
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