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After fertilization the developing mammalian embryo migrates through the oviduct before it implants in the uterus. In order to prevent tubal pregnancy or failed implantation, development and migration of the embryo has to be tightly coordinated1. The precise molecular basis for the regulation of thi...
ORGANISM(S): Mus musculus (Mouse) 
2017-04-04 | PXD003283 | Pride
Uterine receptivity (the window of implantation) is essential for successful implantation. The concept of uterine receptivity was first discovered 50 years ago by Psychoyos. In mice, uterine receptivity begins with the secretion of LIF from uterine glands stimulated by estrogen on the morning of day...
ORGANISM(S): Mus musculus 
2025-02-15 | GSE275806 | GEO
By utilizing Prss29-Cre, Pgr was conditionally deleted to identify the definitive roles of progesterone signaling in the uterine glands during pregnancy. This study provides new insights, demonstrating that PGR-P4 signaling in the glandular epithelium is required for uterine receptivity by regulatin...
ORGANISM(S): Mus musculus 
2025-03-26 | GSE292591 | GEO
Foxa2-dependent uterine glandular cell differentiation is essential for successful implantation
Progesterone receptor in uterine glands is required for pregnancy establishment in mice
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