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ProteomicsSMC Complexes Are Guarded by the SUMO Protease Ulp2 Against SUMO-Chain-Mediated Turnover
Structural maintenance of chromosomes (SMC) complexes, cohesin, condensin and Smc5/6, are essential for viability and participate in multiple processes, including sister chromatid cohesion, chromosome condensation, and DNA repair. Here we show that SUMO chains target all three SMC complexes and are ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-08-05 | PXD022717 | Pride
Condensin Sumo chains Smc5/6 Senp/ulp proteases Cohesin Smc complexes Sumo Slx5/8 Pds5 Stubl-mediated proteasomal degradation 
TranscriptomicsDNA bending facilitates the error-free DNA damage tolerance pathway and upholds genome integrity
DNA replication is sensitive to damage in the template. To bypass lesions and complete replication, cells activate recombination-mediated (error-free) and translesion synthesis-mediated (error-prone) DNA damage tolerance pathways. Crucial for error-free DNA damage tolerance is template switching, wh...
ORGANISM(S): Saccharomyces cerevisiae 
2014-01-28 | E-GEOD-46260 | biostudies-arrayexpress
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