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GenomicsPTK6 domain mutants modulates action in Triple-negative breast cancer
PTK6 domain mutants modulates action in Triple-negative breast cancer
PRJNA658686 | ENA
ProteomicsPTK6 domain mutants modulates action in Triple-negative breast cancer
Protein tyrosine kinase 6 (PTK6; also called Brk) is overexpressed in 86% of breast cancer patients; high PTK6 expression predicts poor outcome. We reported PTK6 induction by HIF/GR complexes in response to either cellular or host stress. However, PTK6-driven signaling events in the context of TNBC ...
ORGANISM(S): Homo sapiens 
2020-08-31 | GSE156676 | GEO
GenomicsPTK6 regulates secretory cell production and innate immunity in a sex-dependent manner in the intestine
PTK6 regulates secretory cell production and innate immunity in a sex-dependent manner in the intestine
PRJNA1017442 | ENA
TranscriptomicsPTK6 regulates secretory cell production and innate immunity in a sex-dependent manner in the intestine
PTK6 regulates regeneration and repair of the intestinal epithelium. Analysis of publicly available datasets showed Ptk6 is upregulated in tuft cells upon activation of type 2 immunity. We found that disruption of Ptk6 influences gene expression involved in intestinal immune responses. Administratio...
ORGANISM(S): Mus musculus 
2024-08-01 | GSE243229 | GEO
UnknownPTEN is a protein phosphatase that targets active PTK6 and inhibits PTK6 oncogenic signaling in prostate cancer.
Not available
S-EPMC5688148 | biostudies-literature
UnknownKinase-Dependent and -Independent Roles for PTK6 in Colon Cancer.
Not available
S-EPMC4912439 | biostudies-literature
UnknownContext-specific protein tyrosine kinase 6 (PTK6) signalling in prostate cancer.
Not available
S-EPMC3602132 | biostudies-literature
UnknownPTK6 regulates IGF-1-induced anchorage-independent survival.
Not available
S-EPMC2909213 | biostudies-literature
UnknownPTK6 inhibits down-regulation of EGF receptor through phosphorylation of ARAP1.
Not available
S-EPMC2923998 | biostudies-literature
UnknownPTK6 activation at the membrane regulates epithelial-mesenchymal transition in prostate cancer.
Not available
S-EPMC3766391 | biostudies-literature
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