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ProteomicsPtprf is the conserved receptor for Asprosin’s glucogenic effects in vertebrates
Asprosin, a fasting-induced glucogenic hormone, plays a crucial role in maintaining glucose homeostasis; however, its receptor remains elusive. This study identifies protein tyrosine phosphatase receptor F (Ptprf) as the receptor mediating Asprosin's metabolic functions. Using zebrafish models, we d...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2026-01-12 | PXD072402 | Pride
Human Insulin receptor Ptprf Mouse Glucose Asprosin Zebrafish 
UnknownPTPRF is disrupted in a patient with syndromic amastia.
Not available
S-EPMC3083333 | biostudies-literature
UnknownLncRNA TCONS_00004099-derived microRNA regulates oncogenesis through PTPRF in gliomas.
Not available
S-EPMC8267291 | biostudies-literature
UnknownMiR-199a-3p Regulates the PTPRF/β-Catenin Axis in Hair Follicle Development: Insights into the Pathogenic Mechanism of Alopecia Areata.
Not available
S-EPMC10743674 | biostudies-literature
GenomicsBurdock miR8175 improves insulin sensitivity in DIO mice by targeting PTP1B and PTPRF [I]
Burdock miR8175 improves insulin sensitivity in DIO mice by targeting PTP1B and PTPRF [I]
PRJNA1037016 | ENA
GenomicsBurdock miR8175 improves insulin sensitivity in DIO mice by targeting PTP1B and PTPRF [II]
Burdock miR8175 improves insulin sensitivity in DIO mice by targeting PTP1B and PTPRF [II]
PRJNA1046073 | ENA
GenomicsBurdock miR8175 improves insulin sensitivity in DIO mice by targeting PTP1B and PTPRF
Burdock miR8175 improves insulin sensitivity in DIO mice by targeting PTP1B and PTPRF
PRJNA1046067 | ENA
GenomicsBurdock miR8175 improves insulin sensitivity in DIO mice by targeting PTP1B and PTPRF [II]
The incidence of type 2 diabetes (T2DM) induced by obesity is rapidly increasing. Although there are many drugs developed for type 2 diabetes, but the anti-diabetic effect of homology of medicine and food is also very popular with the majority of people. Burdock is one such food, but the molecular m...
ORGANISM(S): Arctium lappa 
2024-05-01 | GSE248826 | GEO
TranscriptomicsBurdock miR8175 improves insulin sensitivity in DIO mice by targeting PTP1B and PTPRF [I]
The incidence of type 2 diabetes (T2DM) induced by obesity is rapidly increasing. Although there are many drugs developed for type 2 diabetes, but the anti-diabetic effect of homology of medicine and food is also very popular with the majority of people. Burdock is one such food, but the molecular m...
ORGANISM(S): Mus musculus 
2024-05-01 | GSE247265 | GEO
UnknownInhibition of protein tyrosine phosphatase receptor type F suppresses Wnt signaling in colorectal cancer.
Not available
S-EPMC7606795 | biostudies-literature
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