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This dataset contains two parts of proteomics data: a) the identification and analysis results of co-immunoprecipitation (Co-IP: Flag-asprosin/HA-PFKP) in cardiomyocytes overexpressing Flag-asprosin/HA-PFKP; b) the identification and analysis results of co-immunoprecipitation (Co-IP) using IgG as a ...
ORGANISM(S): Mus Musculus 
2025-12-24 | PXD072385 |
Asprosin Transcription Underlies Obesity Relapse and Inheritance [RNA-seq]
Asprosin Transcription Underlies Obesity Relapse and Inheritance [ATAC-seq]
Asprosin, a fasting-induced glucogenic hormone, plays a crucial role in maintaining glucose homeostasis; however, its receptor remains elusive. This study identifies protein tyrosine phosphatase receptor F (Ptprf) as the receptor mediating Asprosin's metabolic functions. Using zebrafish models, we d...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2026-01-12 | PXD072402 | Pride
Obesity is a unique disease, marked by its near-certain relapse after weight loss and its transmission to offspring of obese mothers. The biological mechanisms behind these phenomena remain elusive. We have found that the obesity-associated cytokine Tgf-β1 activates Fbn1 transcription in adipocytes,...
ORGANISM(S): Mus musculus 
2025-12-31 | GSE277916 | GEO
Obesity is a unique disease, marked by its near-certain relapse after weight loss and its transmission to offspring of obese mothers. The biological mechanisms behind these phenomena remain elusive. We have found that the obesity-associated cytokine Tgf-β1 activates Fbn1 transcription in adipocytes,...
ORGANISM(S): Mus musculus 
2025-12-31 | GSE277913 | GEO
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