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ProteomicsAnalysis of muscular proteomics of deep pressure ulcers reveals JAK2 influence on muscle autophagy and apoptosis
Pressure ulcers (PU) is a complex and serious clinical problem. Deep tissue injury is either the outcome or the trigger of deep PU. However, the cellular and molecular mechanisms that contribute to the pathogenesis of deep PU remain unclear. In this study, the degeneration characteristics, increased...
ORGANISM(S): Homo sapiens (Human) 
2019-11-12 | PXD009512 | Pride
Proteomics Ischemia/reperfusion injury Deep pressure ulcers Jak2 Autophagy & apoptosis 
UnknownTargeting Msx2 as a brake in the fusion fate of osteoclasts and an anabolic therapy in pre-clinical models of osteoporosis.
Not available
S-EPMC12325673 | biostudies-literature
UnknownComprehensive Analysis of Immune Implications and Prognostic Value of SPI1 in Gastric Cancer.
Not available
S-EPMC8882873 | biostudies-literature
UnknownTBX5 and CHD4 Coordinately Activate Atrial Cardiomyocyte Genes to Maintain Cardiac Rhythm Homeostasis.
Not available
S-EPMC12479101 | biostudies-literature
UnknownA nomogram predicting the risk of extrathoracic metastasis at initial diagnosis of T≤3cmN0 lung cancer.
Not available
S-EPMC11384498 | biostudies-literature
UnknownLymph node dissection of station 8 improves the survival of T≤3 cmN0M0 lung adenocarcinoma patients.
Not available
S-EPMC11304141 | biostudies-literature
UnknownThe impact of age on the efficacy of radiotherapy in pleural mesothelioma patients receiving trimodality therapy: a population-based study of the SEER database.
Not available
S-EPMC11565357 | biostudies-literature
UnknownGlobal burden of diabetes in women from 1990 to 2021, with projections to 2050: population-based study.
Not available
S-EPMC12506318 | biostudies-literature
ProteomicsQuantitative proteomic analysis reveals novel function of DDRGK1 in osteosarcoma
DDRGK1 is identified as a target of ufymaltion, while its function in tumor is still largely unknown and even controversial according to recent study. To invesgate the role of DDRGK1 in osteosarcoma, DDRGK1 gene was knockout in 143B cells by CRISPR/cas9, and recombinant DDRGK1 protein was added in t...
ORGANISM(S): Homo Sapiens 
PXD035473 |
ProteomicsPCNA and JNK1-Stat3 pathways respectively promotes and inhibits centrosome amplification by targeting at the ROCK1/14-3-3σ complex
We have recently reported that type 2 diabetes promotes cell centrosome amplification via enhancing the expression, biding and centrosome translocation of ROCK1/14-3-3σ complex. In the present functional proteomic study, we further investigated the molecular pathways underlying the centrosome amplif...
ORGANISM(S): Homo Sapiens 
2018-03-30 | PXD009370 |
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