Pulmonary arterial hypertension

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Pulmonary arterial hypertension (2)
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- (1)
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CHEBI:87614 (1)
CHEBI:21405 (1)

Metabolite Name

Galactonic acid (2)
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L-Malic acid (2)
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Sm d40:1 (1)
Pyrazino[1',2':1,6]pyrido[3,4-b] indole-3-propanoic acid, 1,2,3,4,6,7,12,12a-octahydro-9-methoxy-6-(2-methylpropyl)- 1,4-dioxo-, 1,1-dimethylethyl ester, (3s,6s,12as)- (1)
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NCGC00384653-01 (1)
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N-docosanoyltaurine (1)
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7Z, 10Z, 13Z, 16Z, 19Z-Docosapentaenoic acid (1)
7,8,2'-trihydroxyflavone (1)
6-trans-12-epi-leukotriene b4 (1)
5.beta.-androstan-3.alpha.-ol-17-one sulfate (1)
5,6-isopropylidene-l-ascorbic acid (1)
4-methylabyssinone v (1)
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11-hydroxy-5z,8z,12e,14z,17z-eicosapentaenoic acid (1)

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Modification

57.021464 (1)

Study type

Transcription profiling by array (123)
RNA-seq of coding RNA (14)
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Other (4)
Methylation profiling by array (3)
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Lab affiliation

Pediatric Critical Care Medicine; Developmental Lung Biology and CVP Research Laboratories, School of Medicine, University of Colorado (Aurora, CO, USA). (1)
Full Professor Of Physiology School of Medicine, University College Dublin, School of Medicine, Conway Institute Belfield Dublin 4 (1)
Roy J. Carver Dept. of Biochemistry, Biophysics, and Molecular Biology Iowa State University Ames, IA USA (1)
SFR Necker INSERM US24, Proteomic Platform Necker, France (1)
University of Arizona College of Medicine, Department of Medicine, Division of Endocrinology (1)
Professor, Department of Laboratory Medicine, UCSF (1)
Centre for Pharmacology & Therapeutics (1)
Molecular Biology and Biochemistry, Gottfried Schatz Research Center, Medical University of Graz, Graz, Austria; Institute of Pathology, Diagnostic and Research Center for Molecular Biomedicine, Medical University of Graz, Graz, Austria; Omics Center Graz, BioTechMed-Graz, Graz, Austria (1)
Stanford University, Department of Genetics, United States (1)
Biomedical engineering, Lerner research institue, Cleveland Clinic, Cleveland, OH, USA (1)
Laboratory of Pulmonary Investigation, Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro (1)
Chair of Pharmacology Faculty of Medicine Jagiellonian University Medical College 16 Grzegorzecka Street 31-531 Krakow, Poland tel: +48 12 4211168 fax: +48 12 4217217 (1)
Lecturer School of Cardiovascular and Metabolic Medicine & SciencesKing's College London (1)
Department of Pediatrics, Department of Cell Biology, Neurobiology and Anatomy Medical College of Wisconsin, Milwaukee, WI, United States (1)
Novartis Biomedical Research, Cambridge, MA, USA (1)
EDyP (1)

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Multi-kingdom gut microbiota dysbiosis is associated with the development of pulmonary arterial hypertension

Gut microbiota dysbiosis has been implicated in pulmonary arterial hypertension (PAH). However, most studies have focused on the bacterial community and the exact role and mechanisms of multi-kingdom gut microbiota, including bacteria, archaea and fungi in PAH remains largely unclear. Idiopathic ...

2025-05-12 | MTBLS10563 | MetaboLights

Transcription profiling of human peripheral blood mononuclear (PBMC) cells in pulmonary arterial hypertension

Microarray analysis of peripheral blood mononuclear (PBMC) cells in pulmonary arterial hypertension.

ORGANISM(S): Homo sapiens

2007-09-21 | E-GEOD-703 | biostudies-arrayexpress

Transpulmonary metabolomics in pulmonary arterial hypertension

Not available

ORGANISM(S): Homo sapiens

ST000464 | MetabolomicsWorkbench

Metabolomic heterogeneity of severe pulmonary arterial hypertension

Although multiple gene and protein expression have been extensively profiled in human pulmonary arterial hypertension (PAH), the mechanism for the development and progression of pulmonary hypertension remains elusive. Analysis of the global metabolomic heterogeneity within the pulmonary vascular sy...

ORGANISM(S): Homo sapiens

2014-11-14 | E-GEOD-53408 | biostudies-arrayexpress

The expression of microRNA-30 family in pulmonary arterial hypertension

miRNAs have been proved to participate in the regulation of proliferation and apoptosis in many diseases,we consider there may be associations between miRNAs and development of pulmonary arterial hypertension (PAH). Previous studies have revealed that several miRNAs participated in the regulation of...

ORGANISM(S): Homo sapiens

2021-10-01 | E-MTAB-10932 | biostudies-arrayexpress

Investigation of endothelial cell gene dysregulation in early pulmonary arterial hypertension disease model

Endothelial cell (EC) dysfunction plays a key role in the pathogenesis of pulmonary arterial hypertension (PAH). To avoid cell cultures and whole lung tissue samples, we have, for the first time, used CD31 antibody coated magnetic beads in conjunction with genome scale RNA expression microarrays to ...

ORGANISM(S): Rattus norvegicus

2014-02-06 | E-GEOD-42767 | biostudies-arrayexpress

Acquired chromosome abnormalities in the lungs of patients with Pulmonary Arterial Hypertension (Illumina)

Vascular remodeling in pulmonary arterial hypertension (PAH) involves proliferation and migration of endothelial and smooth muscle cells, leading to obliterative vascular lesions. Previous studies have indicated that the endothelial cell proliferation is quasi-neoplastic, with evidence of monoclonal...

ORGANISM(S): Homo sapiens

2010-05-01 | E-GEOD-21097 | biostudies-arrayexpress

Endothelial DNA methalytion signature in pulmonary arterial hypertension

Pulmonary arterial hypertension (PAH) is a severe and incurable pulmonary vascular disease. One of the primary origins of PAH is pulmonary endothelial dysfunction leading to vasoconstriction, aberrant angiogenesis and smooth muscle cell proliferation, endothelial-to-mesenchymal transition, thrombosi...

ORGANISM(S): Homo sapiens

2016-07-15 | E-GEOD-84395 | biostudies-arrayexpress

Murine Schistosoma-Induced Pulmonary Hypertension: Microarray Data

Rationale: Schistosomiasis is one of the most common causes of pulmonary arterial hypertension worldwide, but the pathogenic mechanism by which the host inflammatory response contributes to vascular remodeling is unknown. We sought to identify signaling pathways that play protective or pathogenic ro...

ORGANISM(S): Mus musculus

2013-07-16 | E-GEOD-48936 | biostudies-arrayexpress

A critical role of microRNAs in human pulmonary arterial hypertension. miR-204: a novel therapeutic target (TaqMan qPCR)

Pulmonary arterial hypertension (PAH) is a vascular remodeling disease characterized by enhanced pulmonary artery smooth muscle cell (PASMC) proliferation and suppressed apoptosis. Downregulation of the BMPR2 gene along with activation of the transcription factor NFAT have been implicated in the mai...

ORGANISM(S): Homo sapiens

2010-12-16 | E-GEOD-21281 | biostudies-arrayexpress

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