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GenomicsPYM1 controls non-canonical EJC occupancy and maintains homeostatic expression of membrance targeted transcripts
PYM1 controls non-canonical EJC occupancy and maintains homeostatic expression of membrance targeted transcripts
PRJNA1222782 | ENA
TranscriptomicsPYM1 controls non-canonical EJC occupancy and maintains homeostatic expression of membrance targeted transcripts
During pre-mRNA splicing in the nucleus, the spliceosome deposits the Exon Junction Complex (EJC) ~24 nucleotides upstream of exon-exon junctions. The EJC core thus deposited comprises of EIF4A3, RBM8A and MAGOH and remains stably bound to RNA to modulate mRNA fate at multiple post-transcriptional s...
ORGANISM(S): Homo sapiens 
2025-07-31 | GSE289360 | GEO
UnknownPYM1 limits non-canonical Exon Junction Complex occupancy in a gene architecture dependent manner to tune mRNA expression.
Not available
S-EPMC12398555 | biostudies-literature
UnknownPYM1 limits non-canonical Exon Junction Complex occupancy in a gene architecture dependent manner to tune mRNA expression.
Not available
S-EPMC11952570 | biostudies-literature
ProteomicsIdentification of Antiviral Roles for the Exon-Junction Complex and Nonsense-Mediated Decay in Flaviviral Infection
West Nile virus (WNV) is an emerging mosquito-borne flavivirus, related to dengue virus and Zika virus. To gain insight into host pathways involved in WNV infection, we performed a systematic affinity-tag purification mass spectrometry (AP-MS) study to identify 259 WNV-interacting human proteins. RN...
ORGANISM(S): Homo sapiens (Human) West Nile virus 
2019-11-14 | PXD011728 | Pride
Nonsense-mediated decay Pym1 Virus-host interactions Exon-junction complex Flavivirus West nile virus 
UnknownIdentification of antiviral roles for the exon-junction complex and nonsense-mediated decay in flaviviral infection.
Not available
S-EPMC6533143 | biostudies-literature
UnknownThe EJC disassembly factor PYM is an intrinsically disordered protein and forms a fuzzy complex with RNA.
Not available
S-EPMC10098021 | biostudies-literature
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