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The complete pool of barcoded homozygous and essential heterozygous diploid deletion strains of S. cerevisiae were screened with 3-nitroso-imidazo[1,2-a]pyridines and -pyrimidines to identify gene deletions that confer sensitivity to each compound.
ORGANISM(S): Saccharomyces cerevisiae 
Hermansen2015 - denovo biosynthesis of pyrimidines in yeast This model is described in the article: Characterizing selective pressures on the pathway for de novo biosynthesis of pyrimidines in yeast. Hermansen RA , Mannakee BK , Knech...
2024-09-02 | BIOMD0000000590 | BioModels
Loss of UXS1 Selectively Depletes Pyrimidines and Induces Replication Stress in KEAP1-Mutant Lung Cancer
Loss of UXS1 Selectively Depletes Pyrimidines and Induces Replication Stress in KEAP1-Mutant Lung Cancer [RNA-seq]
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