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TranscriptomicsPyruvate carboxylase and carbon metabolism in Listeria monocytogenes
Transcriptional profile of wild type L. monocytogenes (EGDe) and a pycA mutant strain was compared on growth in BHI. The human pathogen L. monocytogenes is a facultatively intracellular bacterium that survives and replicates in the cytosol of many mammalian cells. The listerial metabolism, especia...
ORGANISM(S): Listeria monocytogenes 
2010-02-09 | E-GEOD-19014 | biostudies-arrayexpress
ProteomicsRequirement of hepatic pyruvate carboxylase during fasting, high fat and ketogenic diet
Pyruvate has two major fates upon entry into mitochondria, the oxidative decarboxylation to acetyl-CoA or the biotin-dependent carboxylation to oxaloacetate via pyruvate carboxylase (Pcx). Here we have generated mice with a liver specific knockout of pyruvate carboxylase (PcxL-/-) to understand the...
ORGANISM(S): Mus musculus (Mouse) 
2022-10-31 | PXD032028 | Pride
Ketogenesis Acetyl-proteomics Pyruvate carboxylase Mitochondria 
UnknownPyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis.
Not available
S-EPMC4591470 | biostudies-literature
UnknownDifferences between human and rodent pancreatic islets: low pyruvate carboxylase, atp citrate lyase, and pyruvate carboxylation and high glucose-stimulated acetoacetate in human pancreatic islets.
Not available
S-EPMC3099655 | biostudies-literature
UnknownIdentification of carboxylation enzymes and characterization of a novel four-subunit pyruvate:flavodoxin oxidoreductase from Helicobacter pylori.
Not available
S-EPMC177123 | biostudies-literature
UnknownMalic acid production by Saccharomyces cerevisiae: engineering of pyruvate carboxylation, oxaloacetate reduction, and malate export.
Not available
S-EPMC2394876 | biostudies-literature
TranscriptomicsRequirement of hepatic pyruvate carboxylase during fasting, high fat and ketogenic diet
Pyruvate has two major fates upon entry into mitochondria, the oxidative decarboxylation to acetyl-CoA or the biotin-dependent carboxylation to oxaloacetate via pyruvate carboxylase (Pcx). Here we have generated mice with a liver specific knockout of Pcx to understand its role in hepatic mitochondri...
ORGANISM(S): Mus musculus 
2022-10-31 | GSE198317 | GEO
UnknownEffects of eliminating pyruvate node pathways and of coexpression of heterogeneous carboxylation enzymes on succinate production by Enterobacter aerogenes.
Not available
S-EPMC4292478 | biostudies-literature
UnknownDifferential Inhibition of Anaplerotic Pyruvate Carboxylation and Glutaminolysis-Fueled Anabolism Underlies Distinct Toxicity of Selenium Agents in Human Lung Cancer.
Not available
S-EPMC10383978 | biostudies-literature
GenomicsRequirement of hepatic pyruvate carboxylase during fasting, high fat and ketogenic diet
Requirement of hepatic pyruvate carboxylase during fasting, high fat and ketogenic diet
PRJNA814616 | ENA
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