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MetabolomicsUPLC-QE-Orbitrap-MS-Based Metabolomics and Gut Microbiome Analysis to Reveal Codonopsis pilosula (Franch.) Nannf. Extract Improves Cyclophosphamide-Induced Immunosuppression in Mice

Immune system dysfunction leads to recurrent or severe infections, increased susceptibility to concurrent illnesses, and heightened risk of tumors. Current immunomodulators often carry side effects, whereas phytotherapy offers relative stability, making this therapeutic approach worthy of explora...

2026-02-03 | MTBLS13825 | MetaboLights
UnknownComparative analysis of oligosaccharides in the milk of human and animals by using LC-QE-HF-MS.
Not available
S-EPMC10314177 | biostudies-literature
UnknownMetabolomics Analysis of PK-15 Cells with Pseudorabies Virus Infection Based on UHPLC-QE-MS.
Not available
S-EPMC9229976 | biostudies-literature
MetabolomicsComparative metabolomics analysis reveals high-altitude adaptations in a toad-headed viviparous lizard, Phrynocephalus vlangalii
Extreme environmental conditions at high altitude, such as hypobaric hypoxia, low temperature, and strong UV radiation, pose a great challenge to the survival of animals. Although the mechanisms of adaptation to high-altitude environments have attracted much attention for native plateau species, the...
2024-01-16 | MTBLS6900 | MetaboLights
UnknownInsights into the metabolic profiling of Polygonati Rhizoma fermented by Lactiplantibacillus plantarum under aerobic and anaerobic conditions using a UHPLC-QE-MS/MS system.
Not available
S-EPMC9908587 | biostudies-literature
UnknownExtracellular vesicles from melatonin-preconditioned mesenchymal stromal cells protect human umbilical vein endothelial cells against hypoxia/reoxygenation detected by UHPLC-QE-MS/MS untargeted metabolic profiling.
Not available
S-EPMC12171273 | biostudies-literature
UnknownComparative Analysis of Oligosaccharides in Breast Milk and Feces of Breast-Fed Infants by Using LC-QE-HF-MS: A Communication.
Not available
S-EPMC9963387 | biostudies-literature
UnknownExploring ultrasound combined with <i>Litsea pungens Hemsl</i> essential oil compound coating for modulating flavor and metabolites in Nuodeng ham: A multidimensional analysis by UHPLC-QE-MS and GC-IMS.
Not available
S-EPMC12774757 | biostudies-literature
MetabolomicsRich organic nitrogen impacts clavulanic acid biosynthesis through the arginine metabolic pathway in Streptomyces clavuligerus F613-1

Clavulanic acid (CA) is the preferred clinical drug for the treatment of infections by β-lactam antibiotic-resistant bacteria. CA is produced by Streptomyces clavuligerus, and although there have been many reports on the effects of carbon and nitrogen sources on CA production, the mechan...

2022-12-08 | MTBLS5744 | MetaboLights
UnknownIntegrating UHPLC-QE-MS and Bioinformatics with Experimental Validation Reveals MAPK/FOS-Mediated Podocyte Apoptosis as the Key Mechanism of <i>Alpiniae oxyphyllae</i> and <i>Saposhnikovia divaricata</i> in Treating Diabetic Kidney Disease.
Not available
S-EPMC12567254 | biostudies-literature
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