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MetabolomicsDiallyl disulfide (DADS) ameliorates intestinal Candida albicans infection by modulating the gut microbiota and metabolites and providing intestinal protection in mice
Diallyl disulfide (DADS), a garlic extract also known as allicin, has been reported to have numerous biological activities, including anticancer, antifungal, and inflammation-inhibiting activities, among others. Although many studies have assessed whether DADS can treat Candida albicans infec...
2022-05-03 | MTBLS3750 | MetaboLights
MetabolomicsAlterations in the gut microbiota and metabolic profiles coincide with intestinal damage in mice with a bloodborne Candida albicans infection
Candida albicans is an opportunistic fungus that can threaten life especially in patients with candidemia. The morbidity and mortality of candidemia originating from a central venous catheter (CVC) and illicit intravenous drug use (IVDU) are increasing. However, the mechanism underlying the bloodbor...
2021-04-13 | MTBLS1918 | MetaboLights
UnknownChina National Medical Products Administration approval summary: anlotinib for the treatment of advanced non-small cell lung cancer after two lines of chemotherapy.
Not available
S-EPMC6585030 | biostudies-literature
ProteomicsProteomic landscape of serum exosomes to identify potential therapeutic targets.
Using a tandem mass tag (TMT)-based quantitative proteomics approach, we characterized the proteomes of individual patient-derived serum exosomes, identified exosomal protein signatures specific to TNBC patients, and filtered out differentially expressed proteins.
ORGANISM(S): Homo Sapiens 
2021-08-04 | PXD027696 |
ProteomicsBCL2 amplicon loss and super-enhancer remodeling drives ABT-199 resistance
Drug-tolerant “persister” tumor cells underlie the emergence of drug-resistant clones contribute to relapse and disease progression; thus, identifying actionable targets that disable persisters and mitigate relapse are a high priority need. Although the BCL2-targeting agent venetoclax (ABT-199) has ...
ORGANISM(S): Homo sapiens (Human) 
2020-05-26 | PXD010193 | Pride
Abpp Lymphoma Persister Apoptosis 
MetabolomicsMetabolomics Investigation of Dietary Effects on Flesh Quality in Grass Carp (Ctenopharyngodon idellus)

BACKGROUND: The ultra-high density intensive farming model of grass carp (Ctenopharyngodon idellus) may elicit inhibite the growth, decline flesh quality and disease resistance of fish. The quality degradation and excessive fat accumulation in cultured C. idellus have long been a...

2018-08-17 | MTBLS673 | MetaboLights
MetabolomicsThe Genome of Medicinal Plant Macleaya cordata Provides New Insights into Benzylisoquinoline Alkaloids Metabolism
The overuse of antibiotics in animal agriculture and medicine has caused a series of potential threats to public health. Macleaya cordata is a medicinal plant species from the Papaveraceae family, providing a safe resource for the manufacture of antimicrobial feed additive for livestock. The active ...
2017-04-24 | MTBLS435 | MetaboLights
UnknownEvaluation of the therapeutic effects of QuickOpt optimization in Chinese patients with chronic heart failure treated by cardiac resynchronization.
Not available
S-EPMC5844885 | biostudies-literature
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