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TranscriptomicsShp2 Signaling Suppresses Senescence in PyMT-induced Mammary Gland Cancer in Mice [Mouse430_2 array]
In this study, we have used techniques from cell biology, biochemistry, and genetics to investigate the role of the tyrosine phosphatase Shp2 in tumor cells of MMTV-PyMT mouse mammary glands. Genetic ablation or pharmacological inhibition of Shp2 induces senescence, as determined by the activation o...
ORGANISM(S): Mus musculus 
2015-03-06 | E-GEOD-50517 | biostudies-arrayexpress
TranscriptomicsShp2 Signaling Suppresses Senescence in PyMT-induced Mammary Gland Cancer in Mice [Mouse430A_2 array]
In this study, we have used techniques from cell biology, biochemistry, and genetics to investigate the role of the tyrosine phosphatase Shp2 in tumor cells of MMTV-PyMT mouse mammary glands. Genetic ablation or pharmacological inhibition of Shp2 induces senescence, as determined by the activation o...
ORGANISM(S): Mus musculus 
2015-03-06 | E-GEOD-50516 | biostudies-arrayexpress
MetabolomicsTranscriptomics and metabolomics of engineered Synechococcus elongatus during photomixotrophic growth

BACKGROUND: Converting carbon dioxide (CO2) into value-added chemicals using engineered cyanobacteria is a promising strategy to tackle the global warming and energy shortage issues. However, most cyanobacteria are autotrophic and use CO2 as a sole carbon source, which makes it h...

2022-03-21 | MTBLS2825 | MetaboLights
ProteomicsQuantitative proteomics revealed the mechanism of Yiqi Huoxue recipe used to treat cerebral infarction with Qi deficiency and blood stasis
Huoxue Yiqi (HXYQ) recipe is widely used to treat cerebral infarction with Qi deficiency and blood stasis syndrome (CI-QDBS), but its pharmacological mechanism is still not clear. In this study, the serum samples of patients with Qi deficiency and blood stasis syndrome in the convalescent stage of c...
ORGANISM(S): Homo Sapiens 
2022-12-12 | PXD029388 |
TranscriptomicsShp2 Signaling Suppresses Senescence in PyMT-induced Mammary Gland Cancer in Mice
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2015-03-06 | E-GEOD-50518 | biostudies-arrayexpress
UnknownExtract of Plantago asiatica L. Seeds Ameliorates Hypertension in Spontaneously Hypertensive Rats by Inhibition of Angiotensin Converting Enzyme.
Not available
S-EPMC6502967 | biostudies-literature
MetabolomicsAnalysis of flavor formation and metabolite changes during production of buffalo milk Double-Layer Steamed Milk Custard

Metabolomics analysis showed that concentration of free amino acids and short-chain fatty acid lipids were increased in DLSMC, and they were more easily digested and absorbed. Key metabolic pathways, including alanine, aspartate, and glutamate metabolism, starch and sucrose metabolism, and glycer...

2025-08-23 | MTBLS12717 | MetaboLights
UnknownResin Glycosides with <i>α</i>-Glucosidase and Protein Tyrosine Phosphatase 1B Inhibitory Activities from the Seeds of <i>Cuscuta japonica</i>.
Not available
S-EPMC12562854 | biostudies-literature
Unknown<i>Pig-L</i> mediates virulence, biofilm formation, and oxidative stress tolerance in <i>Clostridioides difficile</i>.
Not available
S-EPMC12613277 | biostudies-literature
MetabolomicsIntegrated analysis of faecal microbial diversity and serum metabolome reveals the profiling of gut microbiota-related metabolites in rats and mice prolonged exposure to environmental high humidity

Background: High humidity, as a key climate risk factor, has become one of the significant threats to public health. However, less is known about the mechanism by which the high humidity environment affects the health of the population. The present study was designed to reveal the profile of gut ...

2026-06-16 | MTBLS5660 | MetaboLights
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