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To probe into the molecular mechanism underlying the onset of choroidal neovascularization (CNV), integrated transcriptomic and proteomic analyses of the retinas in mice with laser-induced CNV were performed by using RNA sequencing and tandem mass tag.
ORGANISM(S): Mus Musculus 
2023-02-09 | PXD039971 |
Neovascular AMD (nAMD) and proliferative diabetic retinopathy (PDR) are major blinding retinal diseases characterized by pathological angiogenesis. Using data-independent acquisition (DIA) proteomics, we analyzed aqueous humor from nAMD, PDR, and cataract control patients. Among 3186 identified prot...
ORGANISM(S): Homo Sapiens 
VAMP8 was first identified as an endosomal SNARE that participates in diverse biological functions, including autophagy fusion. We investigated the protein interaction and modification of VAMP8 upon starvation condition compared with normal condition, we thus excised the GFP-VAMP8 band from the Coo...
ORGANISM(S): Homo Sapiens 
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