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MetabolomicsMetabolite signatures of diverse Camellia sinensis tea populations
Tea plants (Camellia sinensis) present an excellent system to study evolution and diversification of specialized metabolites due to their abundance in classes, numbers and contents. A large number of tea cultivars have been cultivated throughout the world not only because of their adaption to differ...
2020-10-05 | MTBLS1405 | MetaboLights
MetabolomicsAirway Dysbiosis Accelerates Lung Function Decline in Chronic Obstructive Pulmonary Disease (Human UPLC-MS/MS assays)

Progressive decline in lung function is a hallmark of chronic obstructive pulmonary disease (COPD). Although airway dysbiosis occurs in COPD, whether it contributes to disease progression remains unknown. Here, through a longitudinal analysis on 181 COPD individuals from two large cohorts involvi...

2023-06-12 | MTBLS5423 | MetaboLights
MetabolomicsAirway Dysbiosis Accelerates Lung Function Decline in Chronic Obstructive Pulmonary Disease (Murine UPLC-MS/MS assays)

Progressive lung function decline is a hallmark of chronic obstructive pulmonary disease (COPD). Airway dysbiosis occurs in COPD, but whether it contributes to disease progression remains unknown. Here we showed, through a longitudinal analysis on two cohorts involving four UK centers, that basel...

2023-06-12 | MTBLS6894 | MetaboLights
MetabolomicsLipidomics profiling reveals the role of glycerophospholipid metabolism in psoriasis
Psoriasis is a common and chronic inflammatory skin disease complicated by genetic-environmental interactions. Although genomic, transcriptomic and proteomic analyses have been performed to investigate the pathogenesis of psoriasis, the role of metabolites in psoriasis, particularly of lipids, remai...
2017-08-22 | MTBLS408 | MetaboLights
ProteomicsPhosphorylation events during systemic acquired resistance in Arabidopsis
Systemic acquired resistance (SAR) is a plant defense response that provides resistance against a wide range of pathogens at the whole-plant level after a primary infection. In this study, we used a data independent acquisition (DIA) phosphoproteomics platform based on the high-resolution mass spect...
ORGANISM(S): Arabidopsis Thaliana 
2021-07-23 | PXD027512 |
ProteomicsComprehensive Analysis of Protein Expression Levels and Phosphorylation Levels in Host Skin in Response to Tick (Haemaphysalis longicornis) Bite
Ticks are widely distributed ectoparasitic arthropods that suck blood from the body surface of livestock, wild animals, and humans. Ticks not only transmit a variety of pathogens but also cause various degrees of damage to their hosts' skin during blood feeding. To explore the molecular regulatory m...
ORGANISM(S): Haemaphysalis Longicornis 
2020-02-24 | PXD017694 |
ProteomicsNafamostat Mesylate Augments Survival in Rats Afflicted by Exertional Heat Stroke
To evaluate the impact of Nafamostat mesylate (NM) in improving survival outcomes among rats subjected to exertional heat stroke.
ORGANISM(S): Mus Musculus 
2025-05-02 | PXD063689 |
ProteomicsAMPK targets PDZD8 to promote carbon source shift to glutamine
This project contains the raw MS data that identified PDZD8 as a substrate of AMPK on the MAM of ER-mitochondria contact. They also revealed that site T527 is an AMPK-phosphorylation site.
ORGANISM(S): Mus Musculus 
2023-04-06 | PXD041428 |
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