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Metabolomicsliquid chromatography-mass spectrometry
Bacterial cells harvested at peak enzyme activity were subjected to untargeted metabolomic profiling to evaluate metabolic changes during straw degradation compared to control (CK) groups. Samples were extracted using pre-chilled methanol–water (4:1, v/v) and analyzed on a UHPLC-Q Exactive HF-X syst...
2026-08-24 | MTBLS15412 | MetaboLights
MetabolomicsHepatic Metabolomics Investigation in Acute and Chronic Murine Toxoplasmosis
Toxoplasma gondii poses a great threat to human health, with no approved vaccine available for the treatment of T. gondii infection. T. gondii infections are not limited to the brain, and may also affect other organs especially the liver. Identification of host liver molecules or pathways involved i...
2019-08-06 | MTBLS586 | MetaboLights
TranscriptomicsIkaros mutation confers integrin-dependent pre-B cell survival and progression to acute lymphoblastic leukemia
Deletion of the Ikaros DNA-binding domain generates dominant-negative isoforms that interfere with Ikaros family activity and correlate with poor prognosis in human precursor B cell acute lymphoblastic leukemias (B-ALL).  Here, we show that conditional inactivation of the Ikaros DNA binding domain i...
ORGANISM(S): Mus musculus 
2014-02-09 | E-GEOD-53401 | biostudies-arrayexpress
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