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UnknownChiglitazar diminishes the warburg effect through PPARγ/mTOR/PKM2 and increases the sensitivity of imatinib in chronic myeloid leukemia.
Not available
S-EPMC11657277 | biostudies-literature
UnknownClinical characteristics of primary parathyroid adenoma and its relationship with coexisting papillary thyroid carcinoma: a clinical retrospective study.
Not available
S-EPMC10240434 | biostudies-literature
TranscriptomicsInitiation Pausing of 80S Ribosome on mRNA Is Governed by 5’UTR and Responsive to mTORC1 Signaling
This SuperSeries is composed of the following subset Series: GSE25331: Initiation pausing of mRNA translation controlled by mTORC1 signaling (microarray) GSE25626: Initiation pausing of mRNA translation controlled by mTORC1 signaling (RNA-Seq) Refer to individual Series
ORGANISM(S): Mus musculus 
2011-11-12 | E-GEOD-25627 | biostudies-arrayexpress
TranscriptomicsStress-dependent CHIP/Daxx interaction suppresses the p53 apoptotic program
Our previous studies have implicated CHIP as a co-chaperone/ubiquitin ligase, whose activities yield protection against stress-induced apoptotic events. In this report, we demonstrate a stress-dependent interaction between CHIP (carboxyl terminus of Hsp70-interacting protein) and Daxx, death domain-...
ORGANISM(S): Mus musculus 
2010-04-03 | E-GEOD-14339 | biostudies-arrayexpress
ProteomicsMouse sertoli cells Palmitoylated protein MS
Elevated palmitic acid, a most abundant saturated fatty acid, is a risk factor for obesity complications. Here, we report that palmitic acid impairs spermatogenesis by inducing abnormal palmitoylation in Sertoli cells. Firstly, we proposed a correlation between palmitic acid and spermatogenesis by r...
ORGANISM(S): Mus musculus (Mouse) 
2022-08-12 | PXD028778 | Pride
Mouse Ms Sertoli cells Palmitoylated protein 
TranscriptomicsInitiation Pausing of 80S Ribosome on mRNA Is Governed by 5’UTR and Responsive to mTORC1 Signaling (Microarray)
Recent studies have revealed that the mRNA translation is punctuated by ribosomal pauses through the body of transcripts. However, little is known about its physiological significance and regulatory aspects. Here we present a multi-dimensional ribosome profiling approach to quantify the dynamics o...
ORGANISM(S): Mus musculus 
2011-11-12 | E-GEOD-25331 | biostudies-arrayexpress
TranscriptomicsInitiation Pausing of 80S Ribosome on mRNA Is Governed by 5'UTR and Responsive to mTORC1 Signaling (RNA-Seq)
Recent studies have revealed that the mRNA translation is punctuated by ribosomal pauses through the body of transcripts. However, little is known about its physiological significance and regulatory aspects. Here we present a multi-dimensional ribosome profiling approach to quantify the dynamics o...
ORGANISM(S): Mus musculus 
2011-11-12 | E-GEOD-25626 | biostudies-arrayexpress
TranscriptomicsHuman transcriptome expression analysis of cervical cancer
Although many protein-coding genes have been identified to be aberrantly expressed in cervical cancer, the mechanisms of development and progression of cervical cancer remain unclear. In recent years, non-coding RNAs, especially including microRNAs and long non-coding RNAs, have been shown to play i...
ORGANISM(S): Homo sapiens 
2014-10-27 | E-GEOD-55940 | biostudies-arrayexpress
ProteomicsDistinct functions of RIPK1 ubiquitination in regulating its activation mediated by TNFR1 and TLRs signaling
We identified and quantified ubiquitination sites of WT RIPK1 and K627R mutant in TNF signaling pathway and 293T overexpression system
ORGANISM(S): Homo Sapiens Mus Musculus 
2020-10-23 | PXD022157 |
ProteomicsIdentification of proteins associated with IFN-γR2 in macrophages
Department of Immunology & Center for Immunotherapy
ORGANISM(S): Mus Musculus 
2018-10-25 | PXD011572 |
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