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We have shown that β-catenin overexpression induced blockage of monocyte-macrophage differentiation by inhibiting PU.1-targeted gene transcription including Egr2 expression in myeloid progenitor cells. Our results suggest that compromised PU.1-targeted gene transcription induced by β-catenin overe...
ORGANISM(S): Mus musculus 
The concentration of blood urea is markedly elevated in patients with advanced chronic kidney disease (CKD). Urea undergoes natural hydrolysis to form cyanate, a reactive species capable of inducing protein carbamylation. To determine whether elevated urea levels promote carbamylation of platelet pr...
ORGANISM(S): Homo sapiens (Human) 
2026-05-28 | PXD067646 | Pride
Gemmatimonas phototrophica is the only phototrophic member of the recently discovered bacterial phylum Gemmatimonadetes. It was isolated from a freshwater lake in the Gobi desert and first described in 2014. So far, Gemmatimonas phototrophica is the only bacterium to have received a complete set of ...
ORGANISM(S): Gemmatimonas phototrophica 
2022-04-04 | PXD024609 | Pride
Urea undergoes natural hydrolysis to form cyanate, a reactive species capable of inducing protein carbamylation. To determine whether elevated urea levels promote carbamylation of platelet proteins, whether this modification is mediated by the urea transporter B (UT-B) expressed on platelets, and wh...
ORGANISM(S): Mus musculus (Mouse) 
2026-05-28 | PXD066058 | Pride
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